Hands-On nerve release could ease common knee pain

NCT ID NCT07318987

Recruiting now Symptom relief Sponsor: Cairo University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a manual therapy technique called saphenous nerve release to see if it can reduce pain, improve balance, and restore function in people with patellofemoral pain syndrome (a common cause of front knee pain). The trial will include 36 adults aged 18 to 35 with persistent knee pain. Researchers will measure changes in pain, balance, and daily function over the study period.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: manual therapy (saphenous nerve release)
What this could lead to: If it works, this could offer a simple, drug-free way to reduce knee pain and improve movement for people with patellofemoral pain syndrome.
What could go wrong: This is a small, early-stage trial with only 36 participants, so results may not apply to everyone. The technique is manual and depends on the therapist's skill, and it may not work for all types of knee pain.

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Conditions

The condition(s) this trial relates to.

Pain patellofemoral pain syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PATELLOFEMORAL PAIN SYNDROME

Contacts and locations

Locations

Faculty of Physical Therapy, Cairo University
RECRUITING

Cairo, Egypt

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