Which exercise retrains the knee best? a Head-to-Head test

NCT ID NCT07766083

First seen Aug 14, 2026 · Last updated Aug 14, 2026

Summary

This study compares two supervised exercise programs—motor control retraining and close kinetic chain exercises—to see which better reduces pain, improves knee function, and strengthens a key thigh muscle in people with patellofemoral pain syndrome (pain around the kneecap). Fifty adults aged 18 to 40 with this condition will be randomly assigned to one of the two programs, attending 45-minute sessions three times a week for six weeks. Researchers will measure pain, knee function, muscle strength, and knee alignment to determine which approach offers greater benefits.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Motor control retraining exercises and close kinetic chain exercises
What this could lead to
If one exercise approach proves more effective, it could give physiotherapists a clearer, evidence-based choice for treating patellofemoral pain syndrome.
What could go wrong
This is a small, early-stage trial with only 50 participants, so results may not apply to everyone. Exercise programs depend on adherence, and outcomes may vary.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Department of Rehabilitation Sciences, The University of Faisalabad

    Faisalabad, Punjab Province, 38000, Pakistan

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Other studies related to the condition(s) this trial covers.