Vitamin E-Infused hip implants face off against ceramic in wear test

NCT ID NCT05175300

First seen Jan 06, 2026

Summary

This study compares two types of hip replacement materials in 100 adults aged 18 to 65 who need a total hip replacement. One group gets a ceramic-on-polyethylene implant where the polyethylene is infused with vitamin E to reduce wear. The other group gets a standard ceramic-on-ceramic implant. The main goal is to measure how much the implant wears down over five years, which could help younger, active patients keep their hip replacements working longer.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Hôpital Privé Jean Mermoz

    RECRUITING

    Lyon, 69008, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Hip replacement device: either a ceramic-on-highly-cross-linked-polyethylene (with vitamin E) or a ceramic-on-ceramic prosthesis

What this could lead to

If successful, this could show that vitamin E-infused polyethylene lasts longer and causes less wear in hip replacements for younger patients, potentially reducing the need for repeat surgeries.

What could go wrong

This is a relatively small study (100 people) and only measures wear over 5 years, not long-term outcomes. The results may not apply to older or less active patients, and both devices are already in use, so no breakthrough is expected.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.