Vitamin E-Infused hip implants face off against ceramic in wear test

NCT ID NCT05175300

Recruiting now Disease control Sponsor: GCS Ramsay Santé pour l'Enseignement et la Recherche Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares two types of hip replacement materials in 100 adults aged 18 to 65 who need a total hip replacement. One group gets a ceramic-on-polyethylene implant where the polyethylene is infused with vitamin E to reduce wear. The other group gets a standard ceramic-on-ceramic implant. The main goal is to measure how much the implant wears down over five years, which could help younger, active patients keep their hip replacements working longer.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Hip replacement device: either a ceramic-on-highly-cross-linked-polyethylene (with vitamin E) or a ceramic-on-ceramic prosthesis
What this could lead to: If successful, this could show that vitamin E-infused polyethylene lasts longer and causes less wear in hip replacements for younger patients, potentially reducing the need for repeat surgeries.
What could go wrong: This is a relatively small study (100 people) and only measures wear over 5 years, not long-term outcomes. The results may not apply to older or less active patients, and both devices are already in use, so no breakthrough is expected.

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Conditions

The condition(s) this trial relates to.

arthropathy osteoarthritis, hip

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HIP ARTHROPATHY

Contacts and locations

Locations

Hôpital Privé Jean Mermoz
RECRUITING

Lyon, 69008, France

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