Which knee exercise works best for anterior knee pain? new study aims to find out

NCT ID NCT07562425

First seen Jun 25, 2026 · Last updated Aug 12, 2026 · Updated 3 times

Summary

This study compares three types of knee-strengthening exercises (isometric, isotonic, and eccentric) in 90 adults aged 18-40 with patellofemoral pain syndrome. Participants will do their assigned exercises three times a week for 8 weeks, alongside standard physiotherapy. Researchers will measure changes in pain, function, and muscle structure using ultrasound and performance tests.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Exercise (isometric, isotonic, or eccentric vastus medialis oblique strengthening)
What this could lead to
If successful, this study could show which type of knee exercise best reduces pain and improves daily function for people with anterior knee pain.
What could go wrong
This is a small, early-stage trial with only 90 participants. Results may not apply to everyone with knee pain, and exercise benefits can vary widely.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Firat University

    RECRUITING

    Elâzığ, MErkez, 23200, Turkey (Türkiye)

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