Patellofemoral pain syndrome
MONDO:0006894A syndrome characterized by retropatellar or peripatellar pain resulting from physical and biochemical changes in the patellofemoral joint. The pain is most prominent when ascending or descending stairs, squatting, or sitting with flexed knees. There is a lack of consensus on the etiology and treatment. The syndrome is often confused with (or accompanied by) chondromalacia patellae, the latter describing a pathological condition of the cartilage and not a syndrome.
109 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsBroader categories
-
Can virtual therapy ease knee pain as well as in-person visits?
Symptom relief OngoingThis study tests whether doing physical therapy from home (via video calls or a mix of home and clinic visits) works as well as going to a clinic in person for young adults with patellofemoral pain syndrome, a common cause of front knee pain. About 42 people aged 18 to 35 will be…
Phase: NA • Sponsor: Cairo University • Aim: Symptom relief
Last updated Jun 27, 2026 13:02 UTC
-
Knee pain relief: targeted exercises show promise in small trial
Symptom relief OngoingThis study tests two types of exercise for people with a common knee condition called patellofemoral pain. One group does neuromuscular control exercises (like balance and coordination), the other does muscle strengthening. Researchers will measure pain, function, and movement in…
Phase: NA • Sponsor: Universidade do Porto • Aim: Symptom relief
Last updated Jun 27, 2026 12:37 UTC
-
Which exercise eases knee pain best? new trial tests two approaches
Symptom relief OngoingThis study compares two exercise programs—closed kinetic chain exercises and isometric exercises—to see which better reduces pain and improves function in women aged 35-60 with patellofemoral pain syndrome and knee osteoarthritis. Seventy participants will be randomly assigned to…
Phase: NA • Sponsor: Dow University of Health Sciences • Aim: Symptom relief
Last updated Jun 27, 2026 12:35 UTC
-
Power up your knees: new exercise program aims to beat chronic kneecap pain
Symptom relief OngoingThis study tests whether a 6-week strength training program that includes power exercises (STRIPE) works better than standard rehab for people with long-term kneecap pain. 88 adults aged 18-40 with pain lasting over 3 months will do supervised telehealth sessions three times a we…
Phase: NA • Sponsor: University of Connecticut • Aim: Symptom relief
Last updated Jun 27, 2026 12:08 UTC
-
Boston marathon study tests online education for Runner's knee
Symptom relief ENROLLING_BY_INVITATIONThis study looks at whether a 6-week, self-guided online education program can help Boston Marathon runners with patellofemoral pain (runner's knee) feel better and run better. About 104 runners will be split into two groups: one gets the program before the marathon, the other af…
Phase: NA • Sponsor: Boston Children's Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 11:00 UTC
-
Weekly Check-Ins could boost patient satisfaction for chronic pain
Knowledge-focused TerminatedThis study looked at whether having more frequent contact with a clinician (at least once a week) improves satisfaction for people with long-lasting musculoskeletal conditions. Participants were split into two groups: one with standard contact and one with extra check-ins via tex…
Phase: NA • Sponsor: University of Texas at Austin • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:06 UTC
-
Can a special clinic get workers back on the job faster? norway launches massive study.
Knowledge-focused OngoingThis study tests whether a Norwegian clinic (NSAC) helps people with common mental health issues or muscle pain return to work sooner. 2500 adults are split into three groups: one gets treatment quickly, one waits 10-14 weeks, and one gets a basic check-up. Researchers will track…
Phase: NA • Sponsor: Nordlandssykehuset HF • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:30 UTC
-
Trail vs. tarmac: which running surface spares your knees?
Knowledge-focused OngoingThis study surveys 134 recreational runners to see if the type of surface they run on (like asphalt or trail) and how much they train is linked to patellofemoral pain, a common knee problem. Participants answer questions about their running habits and any knee pain they've had. T…
Sponsor: University of Oviedo • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:28 UTC
-
Hip implant under the microscope: 5-Year safety study launched
Knowledge-focused OngoingThis study is tracking 120 people who received a HYPE SCS hip stem during total hip replacement. Researchers will monitor how long the implant lasts, how satisfied patients are, and any complications over 5 years. The goal is to confirm the device is safe and works as intended in…
Sponsor: Societe dEtude, de Recherche et de Fabrication • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
-
Massive PT study mines 4 million records to find what works best
Knowledge-focused OngoingThis study looks back at the medical records of about 4 million people who had physical or occupational therapy for muscle and joint problems. Researchers want to see if different ways of giving therapy lead to different results. No new treatments are tested—the goal is to learn …
Sponsor: ATI Holdings, LLC • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:11 UTC
-
Phone app vs. doctor: can a mobile tool catch infections after surgery?
Knowledge-focused TerminatedThis study aimed to see if a mobile monitoring tool could accurately identify surgical site infections (SSIs) in orthopedic surgery patients, compared to the usual manual review. The study was withdrawn before enrolling any participants, so no results are available. It was design…
Phase: NA • Sponsor: Stanford University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:08 UTC
-
Can dry needling rewire the Brain's response to knee pain?
Knowledge-focused OngoingThis study looks at how chronic bilateral knee pain changes the brain's ability to recognize left from right, and whether dry needling can improve movement and muscle function. Sixty adults aged 18 to 40 with patellofemoral pain will be split into groups based on their fear of mo…
Phase: NA • Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:08 UTC
-
Danish knee pain scale gets a scientific makeover
Knowledge-focused OngoingThis study aims to create a Danish version of the Anterior Knee Pain Scale (Kujala), a questionnaire used to assess knee pain and function in people with patellofemoral disorders. Researchers will translate the original English questionnaire into Danish and then test its accuracy…
Sponsor: Aarhus University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC