Patellofemoral pain syndrome
MONDO:0006894A syndrome characterized by retropatellar or peripatellar pain resulting from physical and biochemical changes in the patellofemoral joint. The pain is most prominent when ascending or descending stairs, squatting, or sitting with flexed knees. There is a lack of consensus on the etiology and treatment. The syndrome is often confused with (or accompanied by) chondromalacia patellae, the latter describing a pathological condition of the cartilage and not a syndrome.
109 clinical trials for this condition and its sub-types.
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Knee pain study halted after just one patient
Symptom relief TerminatedThis study aimed to see if using a blood flow restriction cuff during exercise could reduce pain and improve function in people with patellofemoral pain syndrome (front knee pain). The plan was to compare the cuff to a sham (fake) cuff plus standard physical therapy. However, the…
Phase: NA • Sponsor: Gaylord Hospital, Inc • Aim: Symptom relief
Last updated Jun 27, 2026 08:03 UTC
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Knee pain relief through isometric exercises? small study halted early
Symptom relief TerminatedThis study looked at whether a specific set of isometric (holding still) exercises could reduce pain and improve function in people with anterior knee pain. Only 6 people enrolled before the study was stopped early. Participants did exercises like wall sits and glute bridges, and…
Phase: NA • Sponsor: The Methodist Hospital Research Institute • Aim: Symptom relief
Last updated Jun 27, 2026 07:52 UTC
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Scientists gather leftover surgical tissue to unlock secrets of bone disease
Knowledge-focused TerminatedThis study collected bone, cartilage, skin, and fat tissue from 50 patients undergoing surgery at Children's National Medical Center. The goal was to grow cells from these tissues in the lab and analyze them to better understand bone and connective tissue diseases. The study was …
Sponsor: National Institute of Dental and Craniofacial Research (NIDCR) • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC