Knee pain study halted after just one patient

NCT ID NCT05617911

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study aimed to see if using a blood flow restriction cuff during exercise could reduce pain and improve function in people with patellofemoral pain syndrome (front knee pain). The plan was to compare the cuff to a sham (fake) cuff plus standard physical therapy. However, the study was stopped early after only one person enrolled, so no meaningful conclusions can be drawn.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Blood Flow Restriction Cuff

What this could lead to

If it works, this could offer a new therapy option for anterior knee pain that may improve recovery.

What could go wrong

The trial was terminated after enrolling only 1 participant, so results are not reliable. It is unclear if BFR therapy is better than standard care.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for PATELLOFEMORAL PAIN SYNDROME are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

patellofemoral pain syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Gaylord Hospital

    Wallingford, Connecticut, 06492, United States

  • Gaylord Specialty Healthcare Outpatient Physical Therapy; Cheshire

    Cheshire, Connecticut, 06410, United States

  • Gaylord Specialty Healthcare Outpatient Physical Therapy; Cromwell

    Cromwell, Connecticut, 06416, United States

  • Gaylord Specialty Healthcare Outpatient Physical Therapy; Madison

    Madison, Connecticut, 06443, United States

  • Gaylord Specialty Healthcare Outpatient Physical Therapy; Wallingford

    Wallingford, Connecticut, 06492, United States

  • University of Connecticut Health Center

    Farmington, Connecticut, 06030, United States