Knee pain study halted after just one patient
NCT ID NCT05617911
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study aimed to see if using a blood flow restriction cuff during exercise could reduce pain and improve function in people with patellofemoral pain syndrome (front knee pain). The plan was to compare the cuff to a sham (fake) cuff plus standard physical therapy. However, the study was stopped early after only one person enrolled, so no meaningful conclusions can be drawn.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Blood Flow Restriction Cuff
- What this could lead to
- If it works, this could offer a new therapy option for anterior knee pain that may improve recovery.
- What could go wrong
- The trial was terminated after enrolling only 1 participant, so results are not reliable. It is unclear if BFR therapy is better than standard care.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Gaylord Hospital
Wallingford, Connecticut, 06492, United States
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Gaylord Specialty Healthcare Outpatient Physical Therapy; Cheshire
Cheshire, Connecticut, 06410, United States
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Gaylord Specialty Healthcare Outpatient Physical Therapy; Cromwell
Cromwell, Connecticut, 06416, United States
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Gaylord Specialty Healthcare Outpatient Physical Therapy; Madison
Madison, Connecticut, 06443, United States
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Gaylord Specialty Healthcare Outpatient Physical Therapy; Wallingford
Wallingford, Connecticut, 06492, United States
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University of Connecticut Health Center
Farmington, Connecticut, 06030, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Which exercise retrains the knee best? a Head-to-Head test
- Hip and foot moves may ease stubborn knee pain — a trial puts the theory to the test
- A simple hip exercise may boost knee pain recovery — trial puts it to the test
- Can a Hands-On technique boost knee exercise results?
- Simple foot exercise may ease stubborn knee pain in women
- Knee pain showdown: which manual therapy technique wins?