Mononeuropathy

This study looks at people who received a total lumbar disc prosthesis (Baguera®L) for lower back pain or sciatica caused by disc degeneration or herniation. The goal is to see how many return to their original job five years after surgery. Unlike spinal fusion, which often limit…

This study tested whether a drug that blocks TNF-alpha, a protein involved in inflammation and scar formation, can reduce sciatica pain in people who developed spinal scar tissue after back surgery. 38 adults with persistent pain after discectomy received either the drug or a pla…

This study tested whether a diode laser can act as a biomarker to measure neuropathic pain in people with peripheral neuropathy. Researchers compared pain responses to a lidocaine patch versus a placebo patch in 75 participants. The goal was to see if the laser test could disting…

This completed pilot study tested whether shining a low-level laser into the blood (intravenous laser therapy) can improve sleep and reduce pain in people with chronic sciatica. Sixty-six adults with sciatica and poor sleep received either electroacupuncture alone or electroacupu…

This study tested two non-invasive treatments—high-intensity laser therapy and shock wave therapy—for people with cubital tunnel syndrome after an arm burn. 75 adults with healed burns and confirmed ulnar nerve problems received either laser or shock wave therapy plus nerve glidi…

This completed study compared two minimally invasive surgeries for herniated discs: full endoscopic lumbar discectomy (FELD) and microdiscectomy (MD). Researchers enrolled 200 adults aged 18-85 with single-level disc herniation and sciatica. The goal was to see which technique pr…

This study looked at two types of nerve blocks—fascia iliaca block and femoral nerve block—to see which one works better for pain control in people having hip fracture surgery. 80 adults were randomly assigned to receive one of the two blocks before spinal anesthesia. The main go…

This study tested whether an ultrasound-guided injection of sugar water around the sciatic nerve could safely reduce sciatica pain in the emergency department. Researchers enrolled 69 adults with acute sciatica and followed up 72 hours later. The goal was to see if the procedure …

This study tested two non-drug treatments for piriformis syndrome, a condition where a muscle in the buttock presses on a nerve, causing pain. Seventy adults received either low-level laser therapy or radial shockwave therapy, both combined with exercise, over four weeks. Researc…

This study compared two hands-on treatments—post-facilitation stretch and active release technique—for piriformis syndrome in 40 women aged 25 to 45. Researchers measured pain, disability, quality of life, and hip movement over six weeks. The goal was to see which approach offers…

This completed study compared two treatments for piriformis syndrome, a condition causing buttock and leg pain. Forty adults whose pain lasted at least three months were randomly assigned to receive either five sessions of focused sound wave therapy or a single steroid injection.…

This study tested two exercise techniques—dynamic stretching and nerve gliding—in 72 adults with lumbar radiculopathy (nerve-related back pain). Both groups also received standard physiotherapy. The goal was to see which approach better reduced pain and improved daily function ov…

This study tested two physical therapy techniques—nerve gliding exercises and manual muscle release—to see which better relieves sciatica pain. 48 adults with long-term sciatica took part. Researchers measured pain, leg movement, and daily function to find the most effective appr…

This study looked at whether doing hip abductor strengthening exercises could help people with piriformis syndrome feel less pain and move better. 48 adults with the condition took part. The exercises focused on strengthening muscles that move the leg away from the body. The goal…

This study looked at 48 adults with peroneal neuropathy, a condition that causes foot drop and muscle weakness. Researchers compared two treatments: strength training plus taping alone, versus the same plus a special stretching technique called PNF. The goal was to see if adding …

This study compared two physical therapy techniques—neurodynamic mobilization and Mulligan SNAGs—for people with chronic sciatica caused by a disc problem. 66 participants completed the trial at Cairo University. Researchers measured pain intensity, pressure pain threshold, and l…

This study looked at whether adding a muscle relaxation technique (integrated neuromuscular inhibition) to a standard set of strengthening exercises (McGill program) helps people with piriformis syndrome more than the exercises alone. Fifty-six adults with chronic buttock pain fr…

This study tested two local anesthesia methods for hand, wrist, or elbow surgery. One used lidocaine alone, the other added ropivacaine for longer pain relief. 91 adults participated. Researchers measured pain and recovery quality 48 hours after surgery to see if the combination …

This study tested whether a numbing injection near the hip (femoral nerve block) works better than IV fentanyl for pain from a broken hip in the emergency room. 104 adults with hip fractures took part. The goal was to see which method provides faster and more effective pain relie…

This study tested whether manually mobilizing the sacroiliac joint (a joint in the lower back) can reduce tension and pain in the piriformis muscle, a deep hip muscle that often cramps. Researchers used physical therapy techniques on 40 adults with lower back or hip pain and musc…

This study tested two stretching techniques—Post-Isometric Relaxation and Post-Facilitation Stretching—in 36 adults with piriformis syndrome, a condition that causes buttock pain and limits hip movement. Participants did the exercises three times a week for four weeks. Researcher…

This study tested a virtual reality device to see if it could reduce pain in adults with chronic low back pain that didn't respond to medication. 122 participants used the VR system, which creates a 3D environment with changing colors. The main goal was to measure pain levels aft…

This study tested two treatments for meralgia paresthetica, a condition causing pain, numbness, and tingling in the outer thigh. Researchers compared pulsed radiofrequency ablation (using heat to calm the nerve) with steroid injections in 22 adults who did not get relief from sim…

This study tested whether adding gentle nerve gliding exercises (called neurodynamic mobilization) to standard physical therapy could help people with a herniated disc in their lower back. Forty adults with confirmed disc herniation and at least 6 weeks of low back pain took part…

This study tested whether high-power laser therapy can reduce pain and disability in people with sciatica caused by a herniated disc. Thirty-six adults with at least 12 weeks of symptoms received either real or sham laser treatments. The goal was to see if the laser improves pain…

This study looked at how 8 children aged 4 to 17 with moderate foot drop walk when using different supports: barefoot, a Lycra sock, a rigid ankle-foot orthosis (AFO), and a new OrthoPed splint. The goal was to see if the OrthoPed splint allows more natural ankle movement while s…

This study used ultrasound to measure the thickness of certain hip muscles in 60 adults with hip pain on one side (Greater Trochanteric Pain Syndrome) and compared them to healthy people. The goal was to see if muscle thickness differs between the groups and to check for related …

This study used ultrasound to measure the thickness of the piriformis muscle and sciatic nerve in 19 people with piriformis syndrome, comparing the painful side to the pain-free side. The goal was to see if ultrasound can help tell whether the pain comes more from muscle or nerve…

This study tested how different lower-limb prostheses and orthoses affect movement during daily life. Twenty participants with lower-limb amputation or drop foot wore each device for a period while sensors tracked their walking. The goal was to compare devices and improve how we …

This study aimed to find the normal ultrasound size of the ulnar nerve at the elbow in 50 healthy adults. Participants had no history of ulnar nerve problems. Researchers measured the nerve's surface area to establish a reference range, which could help diagnose nerve issues in t…

This study tested whether a device that measures muscle vibrations (mechanomyography) during surgery can predict recovery in 23 patients with cubital tunnel syndrome or peroneal nerve entrapment. Researchers tracked patient-reported outcomes and disability scores after nerve deco…