Kidney disorder
MONDO:0005240A disease involving the kidney.
Also known as: disease of kidney, disease or disorder of kidney, disorder of kidney, kidney disease, kidney disease or disorder, kidney disorder, renal disease, renal disorder
4039 clinical trials for this condition and its sub-types, 223 tagged with Kidney disorder itself.
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Sub-types of Kidney disorder
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Chronic kidney disease 1,096 trials · 1,571 incl. sub-types
6 sub-types
- Chronic renal failure syndrome 835 trials
- End stage renal failure 691 trials
- Diabetic kidney disease 133 trials
- Chronic pyelonephritis 1 trial Sub-types →
- Chronic rapidly progressive glomerulonephritis 1 trial
- Arterionephrosclerosis 0 trials
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Kidney failure 236 trials · 1,393 incl. sub-types
3 sub-types
- Chronic renal failure syndrome 835 trials
- Acute kidney injury 415 trials Sub-types →
- Uremia 16 trials Sub-types →
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Kidney neoplasm 59 trials · 860 incl. sub-types
8 sub-types
- Kidney cancer 244 trials · 851 incl. sub-types Sub-types →
- Childhood kidney neoplasm 1 trial · 30 incl. sub-types Sub-types →
- Renal pelvis neoplasm 1 trial · 24 incl. sub-types Sub-types →
- Kidney benign neoplasm 4 trials · 12 incl. sub-types Sub-types →
- Mesonephric neoplasm 1 trial · 3 incl. sub-types Sub-types →
- Kidney hemangiopericytoma 0 trials
- Mixed epithelial stromal tumor of the kidney 0 trials Sub-types →
- Multiloculated renal cyst 0 trials
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Nephritis 16 trials · 504 incl. sub-types
4 sub-types
- Glomerulonephritis 33 trials · 457 incl. sub-types Sub-types →
- Hereditary nephritis 17 trials · 152 incl. sub-types Sub-types →
- Pyelitis 0 trials · 21 incl. sub-types Sub-types →
- Interstitial nephritis 6 trials · 9 incl. sub-types Sub-types →
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Glomerular disorder 9 trials · 482 incl. sub-types
6 sub-types
- Glomerulonephritis 33 trials · 457 incl. sub-types Sub-types →
- Glomerulosclerosis 1 trial · 51 incl. sub-types Sub-types →
- Immunotactoid or fibrillary glomerulopathy 0 trials · 1 incl. sub-types Sub-types →
- Collagen type III glomerulopathy 0 trials
- Congenital membranous nephropathy due to maternal anti-neutral endopeptidase alloimmunization 0 trials
- Fibronectin glomerulopathy 0 trials Sub-types →
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Inherited kidney disorder 1 trial · 317 incl. sub-types
26 sub-types
- Hereditary nephritis 17 trials · 152 incl. sub-types Sub-types →
- Familial cystic renal disease 0 trials · 72 incl. sub-types Sub-types →
- Inherited renal tubular disease 0 trials · 40 incl. sub-types Sub-types →
- Familial nephrotic syndrome 0 trials · 22 incl. sub-types Sub-types →
- Congenital anomaly of kidney and urinary tract 7 trials · 14 incl. sub-types Sub-types →
- Nephrolithiasis, calcium oxalate 13 trials Sub-types →
- Neurohypophyseal diabetes insipidus 9 trials
- Hereditary renal cell carcinoma 1 trial · 7 incl. sub-types Sub-types →
- Inherited focal segmental glomerulosclerosis 1 trial · 4 incl. sub-types Sub-types →
- Inherited pseudohypoaldosteronism 0 trials · 4 incl. sub-types Sub-types →
- Renal agenesis 1 trial · 2 incl. sub-types Sub-types →
- Liddle syndrome 1 trial Sub-types →
- Hereditary kidney oncocytoma 1 trial
- Prune belly syndrome 1 trial
- Alsing syndrome 0 trials
- Gitelman-like kidney tubulopathy due to mitochondrial DNA mutation 0 trials
- Familial juvenile hyperuricemic nephropathy 0 trials Sub-types →
- Familial renal glucosuria 0 trials
- Fibronectin glomerulopathy 0 trials Sub-types →
- Hypophosphatemic nephrolithiasis/osteoporosis 1 0 trials
- Hypophosphatemic nephrolithiasis/osteoporosis 2 0 trials
- Inherited distal renal tubular acidosis 0 trials Sub-types →
- Nail-patella-like renal disease 0 trials
- Nephrolithiasis, X-linked recessive, with renal failure 0 trials
- Proteinuria, low molecular weight, with hypercalciuria and nephrocalcinosis 0 trials
- Renal tubular dysgenesis of genetic origin 0 trials Sub-types →
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Nephrolithiasis 252 trials · 254 incl. sub-types
3 sub-types
- Nephrolithiasis, calcium oxalate 13 trials Sub-types →
- Acute urate nephropathy 4 trials
- Nephrolithiasis, X-linked recessive, with renal failure 0 trials
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Proteinuria 66 trials · 138 incl. sub-types
2 sub-types
- Hemoglobinuria 1 trial · 73 incl. sub-types Sub-types →
- Proteinuria, low molecular weight, with hypercalciuria and nephrocalcinosis 0 trials
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Impaired renal function disease 109 trials · 129 incl. sub-types
4 sub-types
- Secondary hyperparathyroidism of renal origin 7 trials · 18 incl. sub-types Sub-types →
- Nephrogenic diabetes insipidus 1 trial · 2 incl. sub-types Sub-types →
- Hypophosphatemic nephrolithiasis/osteoporosis 1 0 trials
- Hypophosphatemic nephrolithiasis/osteoporosis 2 0 trials
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Cystic kidney disease 8 trials · 87 incl. sub-types
4 sub-types
- Familial cystic renal disease 0 trials · 72 incl. sub-types Sub-types →
- Multicystic dysplastic kidney 1 trial · 10 incl. sub-types Sub-types →
- Medullary sponge kidney 1 trial
- Non-congenital cyst of kidney 0 trials
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Nephrosis 0 trials · 71 incl. sub-types
1 sub-type
- Nephrotic syndrome 47 trials · 71 incl. sub-types Sub-types →
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Renal infectious disease 16 trials · 64 incl. sub-types
4 sub-types
- Hantavirus hemorrhagic fever with renal syndrome 5 trials · 37 incl. sub-types Sub-types →
- Pyelonephritis 8 trials · 21 incl. sub-types Sub-types →
- Adenovirus renal infection 0 trials
- Renal tuberculosis 0 trials
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Renal tubule disorder 1 trial · 47 incl. sub-types
4 sub-types
- Inherited renal tubular disease 0 trials · 40 incl. sub-types Sub-types →
- Fanconi renotubular syndrome 4 trials Sub-types →
- Renal tubular acidosis 2 trials Sub-types →
- Mucinous tubular and spindle renal cell carcinoma 0 trials
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Diabetes insipidus 34 trials · 38 incl. sub-types
4 sub-types
- Neurohypophyseal diabetes insipidus 9 trials
- Nephrogenic diabetes insipidus 1 trial · 2 incl. sub-types Sub-types →
- Dipsogenic diabetes insipidus 0 trials
- Gestational diabetes insipidus 0 trials
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Renal tubular transport disease 0 trials · 17 incl. sub-types
9 sub-types
- Dent disease 5 trials Sub-types →
- Pseudohypoaldosteronism 3 trials · 5 incl. sub-types Sub-types →
- Fanconi renotubular syndrome 4 trials Sub-types →
- Renal tubular acidosis 2 trials Sub-types →
- Liddle syndrome 1 trial Sub-types →
- Renal hypomagnesemia 3 1 trial
- Bartter syndrome 0 trials Sub-types →
- Gitelman syndrome 0 trials
- Familial renal glucosuria 0 trials
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Stricture or kinking of ureter 9 trials
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Hydronephrosis 7 trials · 9 incl. sub-types
1 sub-type
- Congenital hydronephrosis 3 trials
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Hypertensive nephropathy 8 trials
2 sub-types
- Benign hypertensive renal disease 0 trials
- Malignant hypertensive renal disease 0 trials Sub-types →
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Nephrocalcinosis 7 trials · 8 incl. sub-types
1 sub-type
- Renal hypomagnesemia 3 1 trial
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Renal artery disease 3 trials · 7 incl. sub-types
3 sub-types
- Renal artery atheroma 4 trials
- Renal artery obstruction 3 trials
- Nephrosclerosis 0 trials
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Fetal lower urinary tract obstruction 0 trials · 6 incl. sub-types
5 sub-types
- Posterior urethral valve 5 trials
- Prune belly syndrome 1 trial
- Anterior urethral valve 0 trials
- Atresia of urethra 0 trials
- Urethral obstruction sequence 0 trials
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Congenital primary megaureter 5 trials
5 sub-types
- Congenital primary megaureter, nonrefluxing and unobstructed form 0 trials
- Congenital primary megaureter, obstructed form 0 trials
- Congenital primary megaureter, refluxing and obstructed form 0 trials
- Congenital primary megaureter, refluxing form 0 trials
- Primary megaureter, adult-onset form 0 trials
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Renal hypertension 0 trials · 4 incl. sub-types
3 sub-types
- Renovascular hypertension 4 trials
- Benign renovascular hypertension 0 trials
- Malignant renovascular hypertension 0 trials
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Distal renal tubular acidosis 3 trials
2 sub-types
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Exstrophy-epispadias complex 1 trial · 3 incl. sub-types
4 sub-types
- Bladder exstrophy 3 trials
- Bladder exstrophy-epispadias-cloacal extrophy complex 1 trial
- Cloacal exstrophy 0 trials
- Epispadias 0 trials
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Acute tubulointerstitial nephritis 2 trials
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Kidney cortex necrosis 2 trials
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IgG4-related kidney disease 1 trial
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Anuria 1 trial
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Crush syndrome 1 trial
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Obstructive nephropathy 1 trial
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Orthostatic proteinuria 1 trial
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Renal hypoplasia 1 trial
2 sub-types
- Renal hypoplasia, bilateral 0 trials
- Renal hypoplasia, unilateral 0 trials
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Renal nutcracker syndrome 1 trial
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Arnold stickler bourne syndrome 0 trials
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C1q nephropathy 0 trials
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1 sub-type
- Leiomyoma of vulva and esophagus 0 trials
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Atheroembolism of kidney 0 trials
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Congenital megacalycosis 0 trials
2 sub-types
- Congenital bilateral megacalycosis 0 trials
- Unilateral congenital megacalycosis 0 trials
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Congenital renal artery stenosis 0 trials
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Duplication of urethra 0 trials
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Kidney cortex disease 0 trials
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Kidney hypertrophy 0 trials
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Kidney papillary necrosis 0 trials
1 sub-type
- Acute papillary necrosis 0 trials
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Lachiewicz sibley syndrome 0 trials
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Neonatal renal venous thrombosis 0 trials
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Non-syndromic supernumerary kidneys 0 trials
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Oligomeganephronia 0 trials
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Perinephritis 0 trials
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Pyonephrosis 0 trials
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Renal aminoaciduria 0 trials
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Renal dysplasia 0 trials
2 sub-types
- Renal dysplasia, bilateral 0 trials
- Renal dysplasia, unilateral 0 trials
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Renal tubular dysgenesis 0 trials
3 sub-types
Most studied deeper sub-types
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New team approach aims to simplify care for heart and kidney health
Disease control Not yet recruitingThis study tests a 6-month program where patients work with a pharmacist and their primary care doctor to make shared decisions about medications and lifestyle. The goal is to see if this team-based approach improves heart and kidney health scores and medication adherence. The st…
Early phase 1 • Sponsor: Johns Hopkins University • Aim: Disease control
Last updated Sep 21, 2026 13:00 UTC
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Can a kidney drug stop acute injury from becoming chronic?
Disease control Not yet recruitingThis trial tests whether finerenone, a drug already used for chronic kidney disease, is safe and tolerable for people hospitalized with acute kidney injury (AKI). About 72 adults with moderate-to-severe AKI will receive either finerenone or a placebo once daily for up to 45 days,…
Sponsor: Jean-Maxime Côté • Aim: Disease control
Last updated Aug 22, 2026 00:00 UTC
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A simple letter could spot hidden kidney failure risk before it's too late
Disease control Not yet recruitingThis trial tests whether sending a letter and fact sheet to adults in Manitoba who are at high risk for kidney failure can encourage them to see a kidney specialist. The goal is to catch advanced chronic kidney disease earlier and reduce the number of people who progress to dialy…
Sponsor: University of Manitoba • Aim: Disease control
Last updated Aug 19, 2026 00:00 UTC
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Could a new drug beat the current standard for septic shock?
Disease control Not yet recruitingThis study tests whether a drug called Angiotensin II works better than the usual treatment (norepinephrine) for people with septic shock, a life-threatening condition where blood pressure drops dangerously. About 78 adults with septic shock will receive either Angiotensin II or …
Phase 4 • Sponsor: Wake Forest University Health Sciences • Aim: Disease control
Last updated Jul 26, 2026 00:00 UTC
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Could an allergy drug shield diabetics from organ damage?
Disease control Not yet recruitingThis study tests whether montelukast, a common allergy medication, can reduce damage to the kidneys, eyes, and blood vessels in adults with type 2 diabetes and early kidney disease. The drug works by blocking inflammatory chemicals called leukotrienes, which are linked to diabete…
Phase 4 • Sponsor: University of Colorado, Denver • Aim: Disease control
Last updated Jul 08, 2026 00:00 UTC
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New study: can a smart glucose monitor help diabetics with kidney problems?
Disease control Not yet recruitingThis study tests whether a real-time continuous glucose monitor (CGM) helps people with type 2 diabetes and chronic kidney disease keep their blood sugar in a healthy range. Thirty adults will either use the CGM or stick with standard fingerstick checks for three months. The goal…
Sponsor: Hospital Universitario San Ignacio • Aim: Disease control
Last updated Jun 27, 2026 14:01 UTC
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New drug BHV-1400 aims to protect kidneys in IgA nephropathy
Disease control Not yet recruitingThis Phase 3 trial tests whether BHV-1400 can safely reduce protein in the urine and preserve kidney function in 420 adults with IgA nephropathy. Participants are randomly assigned to receive either the drug or a placebo by injection. The main goal is to see if BHV-1400 lowers pr…
Phase 3 • Sponsor: Biohaven Therapeutics Ltd. • Aim: Disease control
Last updated Jun 27, 2026 13:07 UTC
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Can a diabetes drug stop prediabetes in its tracks?
Disease control Not yet recruitingThis study tests whether glucose-lowering medications (semaglutide and possibly dapagliflozin) can reverse prediabetes and prevent complications like eye, kidney, and nerve damage in people with heart disease. About 158 participants with prediabetes and coronary artery disease wi…
Phase 3 • Sponsor: Michael Mæng • Aim: Disease control
Last updated Jun 27, 2026 09:02 UTC
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Can a community health worker lighten the load for rural caregivers?
Symptom relief Not yet recruitingThis study tests whether a trained community health worker, who provides remote support, can reduce the burden and improve satisfaction for rural caregivers of older veterans with serious illnesses like dementia or cancer. About 480 care partners will be randomly assigned to rece…
Sponsor: VA Office of Research and Development • Aim: Symptom relief
Last updated Sep 11, 2026 00:00 UTC
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Can an ancient herbal remedy soothe the aftermath of stone surgery?
Symptom relief Not yet recruitingThis trial tests whether adding a traditional Chinese herbal decoction, Bushen Huoxue Simiao Formula, to standard care can ease urinary symptoms and improve quality of life for adults recovering from upper urinary tract stone surgery. Participants, aged 18 to 80, will receive eit…
Phase 4 • Sponsor: The Fourth Affiliated Hospital of Zhejiang University School of Medicine • Aim: Symptom relief
Last updated Aug 06, 2026 00:00 UTC
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New study aims to find best pain relief for kids after kidney surgery
Symptom relief Not yet recruitingThis study compares two types of nerve blocks (ESPB and QLB) to see which provides better pain relief for children aged 2-12 after kidney surgery. One hundred children will be randomly assigned to receive one of the two blocks. The main goal is to see how long it takes before the…
Sponsor: Assiut University • Aim: Symptom relief
Last updated Jun 27, 2026 08:11 UTC
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A new tool to predict kidney failure risk in membranous nephropathy?
Knowledge-focused Not yet recruitingThis study is testing whether a prediction model can accurately forecast how quickly kidney function declines in people with primary membranous nephropathy, a kidney disease that can lead to nephrotic syndrome and kidney failure. Researchers will follow 128 adults with biopsy-con…
Sponsor: Assiut University • Aim: Knowledge-focused
Last updated Sep 04, 2026 00:00 UTC
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Blood markers may foretell kidney trouble in lupus
Knowledge-focused Not yet recruitingThis study looks at whether two blood-based inflammation markers, called SII and SIRI, can help track disease activity and predict kidney flares in people with lupus nephritis, a type of kidney inflammation caused by lupus. Researchers will follow 100 adults with confirmed lupus …
Sponsor: Assiut University • Aim: Knowledge-focused
Last updated Aug 26, 2026 00:00 UTC
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Massive kidney trial aims to revolutionize how we test treatments
Knowledge-focused Not yet recruitingAPT-KIDNEY is a large, flexible clinical trial platform designed to test multiple treatments for advanced kidney disease more efficiently. It will enroll up to 5,000 adults with severe kidney problems or those on dialysis. By using electronic health records and adaptive methods, …
Sponsor: Nicholas Carlson • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:07 UTC
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Will a new electronic health record save lives? alberta launches massive study
Knowledge-focused Not yet recruitingThis study looks at whether a new province-wide electronic health record system (called Connect Care) improves outcomes for adults with chronic diseases like diabetes, heart failure, or kidney disease. Researchers will compare hospital readmission and death rates before and after…
Sponsor: University of Calgary • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:37 UTC
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New kidney disease drug candidate tested in healthy people for first time in asia
Knowledge-focused Not yet recruitingThis early-phase trial will test a single dose of the experimental drug GSK4771261 in 30 healthy adults of Chinese, Japanese, and White/European backgrounds. The main goal is to check safety, how the body processes the drug, and whether it causes an immune response. No treatment …
Phase 1 • Sponsor: GlaxoSmithKline • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:35 UTC
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Computer alert aims to catch kidney disease early
Knowledge-focused Not yet recruitingThis study tests whether an electronic health record alert can help primary care doctors refer patients with blood and protein in their urine to a kidney specialist. About 1,200 adults with these high-risk signs will be included. The goal is to see if the alert improves referral …
Sponsor: Geisinger Clinic • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:32 UTC
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Hormone therapy study could unlock kidney disease secrets
Knowledge-focused Not yet recruitingThis study looks at how sex hormones from gender-affirming therapy change kidney function. Researchers will measure kidney performance, blood flow, and insulin sensitivity in 60 transgender people before and after one year of hormone treatment. The goal is to understand why men a…
Sponsor: Amsterdam UMC, location VUmc • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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ER study aims to uncover hidden kidney problems in kids
Knowledge-focused Not yet recruitingThis study will observe 50 children (ages 1 month to 18 years) who come to the emergency room with kidney-related symptoms like swelling, blood in urine, or high blood pressure. Researchers want to learn which kidney diseases are most common and how children respond to initial tr…
Sponsor: Sohag University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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New study eyes monthly virus tests to shield transplant kidneys
Knowledge-focused Not yet recruitingThis study will follow 1000 kidney transplant patients for one year to see if monthly blood tests for certain viruses (CMV, BK, and TTV) can help predict and prevent serious infections and kidney damage. The goal is to learn how the body's immune system and virus levels relate to…
Sponsor: Transplant Genomics, Inc. • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:07 UTC
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Could a simple blood test predict dangerous pregnancy complication?
Knowledge-focused Not yet recruitingThis study will measure a substance called kynurenine in the blood of 204 pregnant women, some with chronic kidney disease and some without. The goal is to see if kynurenine levels are linked to preeclampsia, a serious condition that can harm both mother and baby. Researchers hop…
Sponsor: CHU de Reims • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:06 UTC
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New tool aims to fairly assess older adults for kidney transplants
Knowledge-focused Not yet recruitingThis study tests whether a kidney transplant-specific comprehensive geriatric assessment (KT-CGA) can improve how older adults (60+) are evaluated for kidney transplants. Fifty participants will either receive the KT-CGA plus usual care or usual care alone. The goal is to see if …
Sponsor: Guy's and St Thomas' NHS Foundation Trust • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:05 UTC
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30,000 blood samples could revolutionize rapid disease testing
Knowledge-focused Not yet recruitingThis study will collect blood samples from 30,000 adults in the UK with various health conditions, including blood clots, infections, heart disease, diabetes, and more. The samples will be used to develop and fine-tune new diagnostic tests for the cobas® lumira device, which allo…
Sponsor: LumiraDx UK Limited • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC
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AI takes on dialysis: a smarter way to treat kidney failure in ICUs
Knowledge-focused Not yet recruitingThis study aims to develop and test artificial intelligence (AI) tools to help doctors prescribe and deliver acute dialysis better for patients in intensive care. Researchers will analyze data from 7,500 patients to create algorithms that can predict the best treatment approaches…
Sponsor: University of Alberta • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:10 UTC
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Doctor training may protect kidneys in diabetes patients
Knowledge-focused Not yet recruitingThis study looks at whether training general practitioners to better monitor and manage kidney health can slow the loss of kidney function in people with type 2 diabetes. About 360 patients aged 50 and older with early kidney problems will take part. Doctors in the intervention g…
Sponsor: University Hospital, Lille • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:07 UTC
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Saliva swabs may reveal hidden virus threat in kidney transplants
Knowledge-focused Not yet recruitingThis study tracks BK virus in saliva, urine, and blood of 100 kidney transplant recipients over one year. The goal is to see if the virus spreads through saliva and how it affects the new kidney. Participants collect their own saliva samples at home, plus give urine and blood at …
Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC
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Tiny study probes Glucagon's kidney effects
Knowledge-focused Not yet recruitingThis study will give 10 healthy men glucagon (a blood sugar hormone) and measure kidney blood flow using MRI. Researchers want to see if glucagon changes blood flow in different parts of the kidney and whether blocking certain receptors alters that effect. The goal is to better u…
Sponsor: Bispebjerg Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:53 UTC
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Newborn kidney risk score could save tiny lives
Knowledge-focused Not yet recruitingThis study will check if a tool called the STARZ score can accurately predict acute kidney injury in newborns admitted to the NICU. Researchers will enroll 140 infants and compare the score's predictions to standard tests. If validated, this simple score could help doctors identi…
Sponsor: Assiut University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC
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Does getting older change how your body handles phosphate?
Knowledge-focused Not yet recruitingThis study looks at how age and sex influence the body's ability to manage phosphate after a single oral dose. Forty healthy volunteers in two age groups (18-25 and 63-70) will ingest 558 mg of phosphorus, and researchers will measure phosphate levels in the blood over time. The …
Sponsor: University of Zurich • Aim: Knowledge-focused
Last updated Jun 26, 2026 12:59 UTC