Immunotactoid or fibrillary glomerulopathy
MONDO:0019605A group of very rare glomerular diseases, composed of immunotactoid glomerulopathy (ITG) and non-amyloid fibrillary glomerulopathy (non-amyloid FGP), that are characterized by mesangial deposition of monoclonal microtubular or polyclonal fibrillar deposits. Both present clinically with nephrotic range proteinuria, hematuria and renal insufficiency leading to renal failure in many cases. ITG is more likely to manifest with underlying lymphoproliferative disease, hypocomplementemia, dysproteinemia, monoclonal gammopathy or occult cryoglobulinemia. Non-amyloid FGP is 10 times more frequent than ITG.
Also known as: Immunotactoid or fibrillary glomerulonephritis, fibrillary glomerulonephritis and immunotactoid glomerulopathy
12 clinical trials for this condition and its sub-types.
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Broader categories
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Hope for rare kidney disease: drug trial targets protein leak
Disease control Recruiting nowThis study tests whether obinutuzumab, a drug used for certain blood cancers, can help people with fibrillary glomerulonephritis (FGN), a rare kidney condition that causes protein leakage and can lead to kidney failure. Twenty adults with confirmed FGN will receive the drug intra…
Phase: PHASE2 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated Jun 27, 2026 12:06 UTC
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New study tests which nerve block eases kidney surgery pain best
Symptom relief Recruiting nowThis study compares two types of ultrasound-guided nerve blocks for pain control after open kidney removal surgery. Ninety adults will receive either a rhomboid intercostal sub-serratus plane block or an external oblique intercostal block. Researchers will measure how long it tak…
Phase: NA • Sponsor: Cairo University • Aim: Symptom relief
Last updated Jun 27, 2026 13:07 UTC
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Let it fall? study tests if letting catheters drop out on their own is better than nurse removal
Symptom relief Recruiting nowThis study tests whether letting a bladder catheter fall out on its own (passive removal) is better than having a nurse pull it out (active removal) after urological surgery. 160 men will be randomly assigned to one method. Researchers will measure satisfaction, pain, and anxiety…
Phase: NA • Sponsor: Hospices Civils de Lyon • Aim: Symptom relief
Last updated Jun 27, 2026 11:02 UTC
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New study aims to sharpen diagnosis of malnutrition and kidney disease in seniors
Knowledge-focused Recruiting nowThis study is for older adults, including those in the hospital or with low priority care needs. Researchers want to see if newer methods, like body scans and blood tests, can better detect malnutrition and kidney problems than current standard tests. The goal is to make diagnosi…
Sponsor: Ove Andersen • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:02 UTC
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Can videos and quizzes help patients better understand surgery?
Knowledge-focused Recruiting nowThis study tests a new method to help patients understand complex spine or prostate surgeries before they agree to them. Instead of just reading a form, patients watch multimedia content and answer questions to check their understanding. The goal is to see if this approach makes …
Phase: NA • Sponsor: Istituto Ortopedico Rizzoli • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:01 UTC
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Can AI match doctors? new study puts ChatGPT to the test on urology cases
Knowledge-focused Recruiting nowThis study looks at how well three AI models—ChatGPT, Gemini, and Deepseek—can diagnose and suggest treatments for urology diseases. Researchers will use 800 past patient records from four hospitals to check the AI's accuracy and usefulness. The goal is to understand if AI can he…
Sponsor: First Affiliated Hospital of Fujian Medical University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC