New hope for kidney disease: BHV-1400 trial targets protein leak

NCT ID NCT07642050

First seen Jun 12, 2026 · Last updated Jun 16, 2026 · Updated 2 times

Summary

This study tests whether BHV-1400 can safely reduce kidney damage in people with IgA nephropathy, a disease where antibodies build up in the kidneys. About 420 adults with confirmed IgA nephropathy and high protein in their urine will be randomly assigned to receive either BHV-1400 or a placebo. The main goal is to see if the drug lowers protein levels in urine after one year, which would suggest better kidney health.

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