Circadian rhythm sleep disorder

This study tests whether a personalized lifestyle plan focused on improving diet, exercise, and sleep according to the body's natural rhythms can lower blood sugar levels in older adults. Sixteen participants aged 50-80 with elevated blood sugar and a long daily eating window wil…

This study tests whether the drug idebenone can slow or prevent the progression of a sleep disorder called iRBD into Parkinson's disease or similar brain conditions. About 142 adults aged 40-75 with iRBD will receive either idebenone or a placebo for 5 years. Researchers will tra…

This study tests a new 'intelligent duvet' called Easy Sleep Monitoring (ESM) that uses built-in sensors to detect movement and estimate sleep. Researchers will compare its accuracy to standard sleep lab tests (video-polysomnography) in 50 people, including those with sleep disor…

This study tests whether a special type of talk therapy for insomnia (CBT-I) that is customized for shift workers can improve sleep, mental health, and quality of life. About 84 healthcare workers who work rotating shifts including nights will either receive this tailored therapy…

This study looked at whether sunlight exposure therapy could improve sleep problems in people with Alzheimer's disease. Sixty participants with mild Alzheimer's and sleep issues received a health education plan on sun exposure and were followed for 14 days. The goal was to see if…

This study is testing whether special drug-free patches can help relieve acute back, shoulder, or other muscle pain and improve sleep. The patches use a gentle vibration technology instead of medication. 150 adults aged 18-64 will wear either an active patch or a sham (fake) patc…

This study tests whether a program called the Model of Occupational Harmony (MOHar) can help people with sleep disorders sleep better and feel better. Forty adults with poor sleep will either get this program—which helps them redesign their daily routines with an occupational the…

This study looks at how the body's internal clock (circadian rhythm) affects heart disease risk, especially in people with obesity. Researchers measured blood pressure and other heart markers in 17 lean and overweight adults over 5 days. The goal is to understand if obesity creat…

This study looks at whether people with memory problems will wear and use digital devices like smartwatches, sleep headbands, and smartphone apps to collect health data. Researchers will combine this data with clinical information to build machine learning models that might one d…

This pilot study aimed to see if personalized lifestyle coaching and a simple handout could help emergency medicine residents stay alert and perform better during night shifts. The study planned to compare coached residents to those receiving only a handout, measuring reaction ti…

This study uses a 30-40 minute online survey to understand how being on call affects sleep in 1,000 medical trainees (students, residents, fellows). It looks at sleep quality, quantity, and disruption to body rhythms. The goal is to gather knowledge to improve sleep health for he…

This study looks at how working night shifts changes eating behaviors and appetite compared to day shifts. Researchers will measure food intake, hunger hormones, and fullness in 100 healthy adults who work either day or night shifts. The goal is to understand why night workers ar…

This study looks at whether doing brain-training exercises in the morning or the afternoon helps older adults (60+) recover thinking skills after a stay in the intensive care unit. Forty participants will either train in the morning, in the late afternoon/evening, or receive usua…

This study looks at how sleep and your internal body clock influence blood pressure at night. Researchers will monitor over 1,400 participants using a constant routine protocol—staying awake in a dim room for over 24 hours—to measure melatonin, body temperature, and blood pressur…

This study looks at whether eating a high-carb or high-protein dinner 3-4 hours before bed can help medical residents sleep better. 90 participants will be assigned to one of three meal types for two weeks. Sleep quality will be measured using questionnaires and smartwatches, and…

This study tests a sleep-health program that uses habit-formation science to help young adults (ages 18-30) improve their sleep. Researchers want to see if adding text message reminders makes it easier for people to stick with healthy sleep routines. The goal is to find simple, e…

This study looks at how problems with the body's internal clock (circadian rhythm) may contribute to REM sleep behavior disorder (RBD), a condition where people physically act out their dreams. Researchers will measure melatonin levels and sleep patterns in 30 adults recently dia…

This study looks at how sleep problems like apnea, insomnia, and poor sleep quality are linked to heart disease and diabetes in rural southern areas. About 3,680 adults already in a larger health study will wear sleep trackers and answer questionnaires. The goal is to understand …