Non-24-hour sleep-wake syndrome
MONDO:0019137Non-24-hour sleep-wake disorder (non-24 disorder), also known as hypernychthemeral syndrome, is a circadian rhythm sleep disorder characterized by non-synchronization to a 24-hour day leading to insomnia and daytime sleepiness with sometimes severe associated manifestations.
Also known as: Non-24-Hour Sleep-Wake Disorder, circadian rhythm sleep disorder, free running type, circadian rhythm sleep disorder, free-running type, hypernychthemeral syndrome, non-24, non 24 hour sleep wake disorder
19 clinical trials for this condition and its sub-types.
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Could a wearable device replace hospital sleep tests for kids with cerebral palsy?
Diagnosis Recruiting nowThis study is testing whether simple wearable devices can accurately screen for sleep disorders in children with cerebral palsy. About 140 children aged 6 to 15 will wear the devices at home and then undergo a standard hospital sleep test. The goal is to see if the wearable metho…
Phase: NA • Sponsor: University Hospital, Brest • Aim: Diagnosis
Last updated Jun 27, 2026 14:02 UTC
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Could a headset fix sleep problems in the blind? new trial tests Nerve-Stimulating device
Symptom relief Recruiting nowThis pilot study tests whether a non-invasive headset that delivers mild electrical stimulation to nerves behind the ear can safely improve sleep in adults who are blind or severely sight impaired. Sixty participants will use the device for 30 minutes a day, five times a week for…
Phase: NA • Sponsor: Neurovalens Ltd. • Aim: Symptom relief
Last updated Jun 27, 2026 12:07 UTC
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Medical cannabis under the microscope: 1,000 patients tracked for Real-World relief
Symptom relief Recruiting nowThis study follows 1,000 adults in Canada who are authorized to use medical cannabis for pain, sleep issues, anxiety, depression, or epilepsy. Researchers will track changes in symptoms using standard questionnaires over 24 weeks. The goal is to see how well medical cannabis work…
Sponsor: University Health Network, Toronto • Aim: Symptom relief
Last updated Jun 27, 2026 12:02 UTC
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Can a 4-Week online course tame your night terrors?
Symptom relief Recruiting nowThis study tests a 4-week online course designed to help adults who experience parasomnias—unwanted sleep events like sleep terrors, sleepwalking, and nightmares. The course teaches safety planning, relaxation, and therapy techniques. Researchers will measure whether it reduces h…
Phase: NA • Sponsor: University of Manitoba • Aim: Symptom relief
Last updated Jun 27, 2026 08:13 UTC
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Memory tricks may help older adults finally get a good Night's sleep
Symptom relief Recruiting nowThis study tests whether a special memory support program can help people aged 50 and older remember and stick to their sleep treatment. The program uses simple memory strategies alongside standard sleep therapy. Researchers will track sleep quality, daily functioning, and life s…
Phase: NA • Sponsor: University of California, Berkeley • Aim: Symptom relief
Last updated Jun 27, 2026 07:59 UTC
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Amino acid supplement tested for better sleep in brain injury
Symptom relief Recruiting nowThis study tests whether taking branched chain amino acids (BCAAs) twice a day for three weeks can improve sleep in people with traumatic brain injury. Researchers will also check if the supplement is easy to take and if participants stick with it. The study involves 300 veterans…
Phase: NA • Sponsor: Portland VA Medical Center • Aim: Symptom relief
Last updated Jun 27, 2026 07:57 UTC