Scientists probe nighttime blood pressure: could your sleep schedule be the key?

NCT ID NCT05656768

ENROLLING_BY_INVITATION Knowledge-focused Sponsor: University of Alabama at Birmingham Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at how sleep and your internal body clock influence blood pressure at night. Researchers will monitor over 1,400 participants using a constant routine protocol—staying awake in a dim room for over 24 hours—to measure melatonin, body temperature, and blood pressure. The goal is to better understand why nighttime blood pressure varies, which could lead to improved prevention or treatment of hypertension.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could help explain why some people have high blood pressure at night and point to new ways to manage it.
What could go wrong: This is an observational study, not a treatment trial. It will not directly test any therapy, and results may not lead to immediate changes in care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

circadian rhythm sleep disorder hypertensive disorder sleep disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BLOOD PRESSURE CIRCADIAN RHYTHM HYPERTENSION SLEEP

Contacts and locations

Locations

University of Alabama at Birmingham

Birmingham, Alabama, 35294-0017, United States

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