Vastra Gotaland Region

This study looks at whether adding focused, high-dose radiation to standard drug therapy can help people with non-small cell lung cancer that has spread to a few spots (up to 5). About 240 participants will be randomly assigned to get either standard treatment alone or standard t…

This study compares two ways of using laser treatment for proliferative diabetic retinopathy, a leading cause of blindness in working-age adults. Researchers will give 40 participants either a single laser session or multiple sessions to see which is safer and works better. The g…

This study compares two treatments for arm and hand spasticity (muscle stiffness) caused by stroke, spinal cord injury, or brain injury. Thirty adults who already get Botox injections will also receive corrective surgery, allowing doctors to see which approach works better for ea…

This study tests a special program (LAGOM) designed to improve heart health and quality of life for people with psychotic disorders. 644 adults from six clinics in Gothenburg will take part; some get the program, others get usual care. The program includes regular check-ups, body…

This study compares a paclitaxel-coated balloon (Optilume) to a standard balloon for treating recurrent urethral stricture, a narrowing of the urine tube. About 230 adults who have had at least one prior treatment will be randomly assigned to one of the two balloons. The goal is …

This study looks at whether creating a personalized care plan for people with COPD after they leave the hospital can help them stay healthier and avoid future hospital visits. About 110 adults who smoke or used to smoke will get a thorough check-up and a custom plan that may incl…

This study tests whether adding another chemotherapy drug (lomustine) to the standard treatment can help people with a specific type of glioblastoma, a fast-growing brain cancer, live longer. About 200 adults aged 18-70 with newly diagnosed, MGMT-methylated glioblastoma will be r…

This study tests whether one dose of the immunotherapy drug pembrolizumab, given before standard surgery, can shrink or eliminate tumors in people with stage IIb/c melanoma. About 30 adults with thick melanomas that haven't spread to lymph nodes will receive either pembrolizumab …

This study tests a program called WOMENinMOTION that teaches pregnant women how to manage pelvic girdle pain through education, exercise, and pain coping strategies. The goal is to help women stay physically active during pregnancy and prevent chronic pain that can last for years…

This study tests whether a tailored physical activity plan, guided by a physiotherapist, can improve quality of life, fitness, and fatigue in people who had surgery for a non-functioning pituitary adenoma. About 120 participants will be randomly assigned to either receive the per…

This study looks at two different recovery plans after surgery for peroneal tendon injuries (torn tendons on the outer ankle). About 50 adults in Gothenburg, Sweden, will be randomly assigned to one plan. Researchers will measure pain, movement, and strength before and after surg…

This study tests whether a person-centred care (PCC) program, delivered by phone and online, can reduce mental fatigue and sick leave in 220 adults with Graves' disease. Participants will either receive usual care or usual care plus the PCC program. The goal is to see if this app…

This study tests whether a special course on managing mental fatigue can improve brain fog, exhaustion, and quality of life in people with Graves' disease. About 96 adults with persistent mental fatigue will either take the course plus standard care or receive standard care alone…

This study follows 380 women for one year after vaginal childbirth to see how pelvic floor muscles and tissues recover. It also tests whether early, personalized pelvic floor muscle training can improve symptoms like urine leakage, bowel issues, and vaginal bulging compared to st…

This study tests a short therapy program (ASSIP-OA) designed to prevent suicide in adults aged 65 and older who have recently attempted suicide or had serious suicidal thoughts. About 132 participants will receive either the program plus usual care or usual care alone. Researcher…

This study looks at giant cell arteritis, a condition that causes inflammation in blood vessels and is common in older adults. Researchers want to find better ways to predict who will have a relapse and how well treatment is working. They will use ultrasound scans and blood tests…

This study talks to parents of 12 to 15 children with functional constipation to learn how physical activity might help. The goal is to understand parents' views and experiences, since there is little research on this topic. The results could lead to better care and possibly invo…

This study looks at 150 people with diabetic macular edema (DME) to see if certain markers in the blood and eye scans can predict how well they respond to two common treatments: anti-VEGF injections or a dexamethasone implant. Participants will be divided into groups based on the…

This study tests a new camera-based system that measures pulse, blood pressure, breathing rate, oxygen levels, and body temperature without touching the patient. The goal is to see if it works as well as current devices that require physical contact, which can spread infections. …

This study looks at whether changing who first sees a patient with a sore throat can cut down on unnecessary antibiotic prescriptions. Researchers will compare what happens when a doctor, a trained nurse, or a trained pharmacist does the initial check. The goal is to see if this …

This study follows 400 people who have urologic cancer surgery with lymph node removal to see how often leg swelling (lymphedema) happens. Researchers use questionnaires and special devices to measure swelling and tissue fluid over two years. The goal is to better understand this…

This study aims to understand why some people with Graves' disease continue to experience mental fatigue even after their thyroid levels return to normal. Researchers will compare blood and spinal fluid samples from 180 participants—60 with mental fatigue, 60 without, and 60 heal…

This study looks at 300 women aged 50 and older who have blood in their urine along with a bladder infection. Researchers want to see if these women need the full set of cancer tests (like a camera in the bladder and CT scans) or if they can safely skip them. The goal is to find …

This study tests a magnetic tracer and clip to help surgeons locate lymph nodes in breast cancer patients before chemotherapy. About 459 adults will receive the injection before surgery to see how well it works. The goal is to improve detection and reduce the need for more invasi…