Vastra Gotaland Region

This study aims to find the most effective and cost-friendly way to treat children with prominent front teeth (overjet). Researchers will compare three early treatment options—headgear, twin blocks, and clear aligners—against waiting and using traditional braces later. The trial …

This study is testing whether a combination of chemotherapy and radiation can effectively treat early rectal cancer, allowing patients to avoid major surgery that often leads to permanent bowel problems. Patients can choose between standard surgery or this organ-preserving treatm…

This early-stage study is testing a personalized treatment for advanced melanoma that has spread. Doctors will collect a patient's own tumor-fighting immune cells, grow them in a lab, and then return them either directly to the liver area or into the bloodstream. The main goals a…

This study tests whether personalized video coaching can help adult survivors of childhood cancer improve their health and quality of life. Researchers will work with 900 survivors who have unhealthy lifestyles, offering 26 weeks of coaching focused on physical activity and diet.…

This study tests whether giving dry plasma (a powder that helps blood clot) during ambulance transport improves survival for people with severe bleeding from injuries, childbirth complications, or internal bleeding. Researchers will compare dry plasma against standard IV fluids i…

This study is testing a faster version of a non-invasive brain stimulation treatment for depression. It aims to see if giving 30 treatment sessions over just 5 to 14 days is effective and tolerable for patients. Researchers will enroll up to 150 people with depression to measure …

This study aims to understand how the pelvic floor muscles and tissues heal during the first year after a vaginal birth. It will track 380 new mothers to see how physical changes relate to symptoms like incontinence and prolapse. A smaller group with symptoms will test if startin…

This study is testing a special diet adapted for Nordic countries to see if it can help children with Crohn's disease achieve remission. Researchers will compare results from 30 children on this new diet to past results from a standard diet. The goal is to see if the Nordic versi…

This study is testing two digital tools to help family doctors diagnose ear infections more accurately. One is a game-like training app for doctors, and the other is an AI system that analyzes ear images. The goal is to see if these tools help doctors make better decisions, which…

This study aims to see if a new type of knee assessment, focusing on simple movements like standing up from a chair, works as well as traditional hands-on tests. Researchers will compare diagnoses made during video calls to those made during in-person visits with a physiotherapis…

This study aims to develop better tools for managing Giant Cell Arteritis (GCA), a serious blood vessel inflammation. Researchers will test if combining a detailed ultrasound scan of arteries with new blood tests can more accurately predict which patients are at high risk of the …

This study aims to develop a better way to help teenagers improve their daily brushing and flossing to prevent gum disease. Researchers will test a mobile health app and follow-up video calls with a dental hygienist to see if they help motivate and support 16-17 year olds in buil…

This study is testing whether a 12-week program of high-intensity aerobic and strength training can improve heart health, fitness, and overall well-being in people with psoriatic arthritis. Researchers will enroll 88 adults to see if this exercise plan can reduce inflammation, pa…

This European study aims to improve the understanding and diagnosis of non-progressive congenital ataxia, a rare movement disorder in children. Researchers will observe 50 children aged 5 to 8 years old, collecting detailed information about their symptoms, brain scans, and genet…

This study aims to measure how often pressure monitors in intensive care units (ICUs) are slightly misaligned, which can lead to incorrect readings. Researchers will observe 60 critically ill adult patients on breathing machines who have special catheters for monitoring blood pre…

This study aims to understand how different pressure settings on a breathing machine affect the lungs and breathing muscles of patients in the intensive care unit. Researchers will test three pressure levels on 25 patients who are on a specific type of ventilator support. The goa…

This study aims to understand if being very flexible (hypermobile) is common in young females with anorexia and if it helps explain why some experience pain. It also looks at whether jaw joint problems make eating more difficult. Researchers will examine 100 participants and ask …

This study looks at whether sending a medical team to treat seniors at home during a health emergency works as well as sending them to the hospital emergency room. It will track 5,000 people aged 75 and older to see if home care leads to similar rates of hospital admission and su…

This study aims to see if a simple exercise bike test gives consistent results for people with hip or knee osteoarthritis. Forty patients on a waiting list for arthritis rehab will take the same test twice, 1-2 weeks apart. The goal is to check if the test is reliable, which is n…