Vastra Gotaland Region

This study tests a 26-week video coaching program to help adult survivors of childhood cancer eat better and be more active. The goal is to improve quality of life and reduce long-term health risks like heart disease. About 900 survivors with unhealthy lifestyles will take part, …

This early-stage trial tests a treatment that uses immune cells taken from a patient's own tumor to fight metastatic melanoma. The cells are grown in a lab and then given back to the patient either directly into the liver or through a vein. The study will check if this approach i…

This study will enroll 144 children aged 9-13 with Class II malocclusion (where the upper jaw sticks out) and a large overjet. Participants will be randomly assigned to one of three early treatments (headgear-activator, twin-block, or Invisalign mandibular advancement) or a contr…

This study tests a modified version of the Crohn's Disease Exclusion Diet (CDED) in 30 children aged 6-18 with mild-to-severe Crohn's disease. The goal is to see if the Nordic CDED can help children achieve remission without steroids, while also improving diet adherence and quali…

This study tests whether giving dry plasma to people with life-threatening bleeding before they reach the hospital can improve survival. Researchers will compare dry plasma to standard fluids in 650 adults with signs of bleeding shock. The goal is to see if this approach reduces …

This study is for people with early-stage rectal cancer. It tests whether using chemoradiotherapy (a combination of chemotherapy and radiation) can completely eliminate the tumor, allowing patients to safely avoid surgery and keep their rectum. Participants can choose between sta…

This study tests two digital tools to help primary care doctors diagnose ear infections more accurately. One is a game-like training program for physicians, and the other is an AI system that analyzes ear images. About 200 patients with ear symptoms will take part across four Swe…

This study looks at a rare condition called non-progressive congenital ataxia, which affects movement and coordination in young children. Researchers will use detailed checkups, brain scans, and genetic tests to better understand the condition and improve diagnosis. The goal is t…

This study looks at whether a physiotherapist can accurately diagnose knee pain through a video call instead of an in-person visit. Researchers will compare diagnoses made using a function-based assessment (no special tests) in both settings. The goal is to see if video consultat…

This study tests whether a magnetic tracer (Magtrace) works as well as the standard radioactive dye plus blue dye for finding sentinel lymph nodes in people with melanoma. About 254 adults will get both tracers before surgery, and doctors will compare how often each method finds …

This study looks at whether 12 weeks of high-intensity interval training and strength training can improve heart function, metabolism, and inflammation in people with psoriatic arthritis. About 88 adults aged 18-65 with stable medication will participate. The goal is to see if ex…

This study is testing a faster version of a brain stimulation treatment called iTBS for people with depression. Instead of the usual schedule, participants will receive 30 short sessions over 5 to 14 days. The goal is to see if this quicker approach works well and is tolerable in…

This study will look at 5,000 people aged 75 and older who had an acute illness. It compares those who received care at home from a mobile healthcare team to those who went to the emergency department. The goal is to see if home-based care is just as good at reducing the need for…

This study aims to see if a short, submaximal bike test (the Ekblom-Bak test) gives consistent results when repeated in people with hip or knee osteoarthritis. Forty patients from a Swedish OA program will take the test twice, one to two weeks apart. If reliable, this test could …

This study explores whether a health app and follow-up video chats with a dental hygienist can motivate teenagers (ages 16-17) to improve their oral hygiene and reduce gingivitis. About 25 teens with gum inflammation will test the approach. The goal is to see if this digital meth…

This study will check how common joint hypermobility (being very flexible) and pain are in 100 females aged 13-25 with anorexia. Researchers want to see if hypermobility or jaw problems make eating harder or cause pain. Participants fill out questionnaires and have their joint mo…

This study aims to learn how adults with Fabry disease who are not yet receiving treatment experience their quality of life. Researchers will interview 35 participants in Sweden to hear about symptoms, daily life, and healthcare experiences. The goal is to identify unmet needs an…

This study watches 300 premature babies born before 37 weeks who need surfactant—a natural substance that helps their immature lungs stay open. Doctors will use different methods to give the medicine (like a thin tube or a mask) as part of normal care. The goal is to see which me…

This study looks at how different levels of pressure from a breathing machine (ventilator) affect the lungs and diaphragm in 25 ICU patients with respiratory failure. Each patient will try three pressure settings to see which one helps them breathe more efficiently and with less …

This study will check how often the blood pressure monitors in the ICU are not positioned correctly, which can lead to wrong readings. Researchers will watch 60 critically ill adults on breathing machines and blood pressure support for 8 hours. They will see if these small errors…