Vastra Gotaland Region

This phase 2 trial tests whether taking capsaicin, the compound that gives chili peppers their heat, can desensitize the cough reflex and reduce symptoms in people with chronic idiopathic cough, a persistent cough with no identifiable cause. About 55 adults with this condition wi…

This trial is testing whether a minimally invasive version of isolated limb perfusion is feasible. Isolated limb perfusion is a procedure that delivers high-dose chemotherapy directly to a limb affected by cancer, but the standard approach requires a large incision. The study wil…

This trial tests whether a 'physical activity on prescription' (PAP) program can help children aged 6-12 with obesity become more active. Over 4 months, children choose activities they enjoy and follow a written prescription for how often and how long to do them. Researchers will…

This study looked at over 17,000 people who had a heart attack to compare two blood thinners: prasugrel and ticagrelor. Hospitals switched from ticagrelor to prasugrel in a stepwise way to see which drug better prevents death, another heart attack, or stroke. The goal is to find …

This study tested whether giving the drug durvalumab after precise radiation therapy (SBRT) helps people with early-stage lung cancer stay cancer-free longer. About 106 patients with stage I non-small cell lung cancer who could not have surgery or chose not to were randomly assig…

This early-phase trial tested a combination of two drugs—177Lu-DOTA-TATE (a radioactive therapy) and olaparib (a PARP inhibitor)—in 18 people with certain cancers like neuroendocrine tumors, thymoma, or mesothelioma that have a specific marker (somatostatin receptor). The goal wa…

This study looked at whether using only ticagrelor (a blood thinner) after heart attack stenting is safe, instead of the usual two-drug combination. It included 200 adults who had a stent placed during a heart attack. The main goal was to check for serious heart problems or stent…

This early-phase trial tested whether it is safe and feasible to give patients their own immune cells (called tumor infiltrating lymphocytes, or TIL) directly into the liver artery. Eight adults with melanoma that had spread to the liver received the TIL infusion along with chemo…

This study tests a program called 'Thoughts and Health' designed to prevent depression in adolescents. The program is delivered in 12 sessions in a school setting. Researchers will see if it helps students' mental health and their ability to finish junior high with passing grades…

Many adults with ADHD still struggle with inattention, planning and impulsivity even after medication. Researchers are testing whether group cognitive behavioural therapy helps more than a structured activity group. About 226 adults with ADHD join weekly two-hour sessions for 12 …

This study tested whether a home-based exercise program using an exergaming (video-game exercise) system, supervised remotely by a physiotherapist, could improve physical fitness and quality of life in people with COPD. 92 participants were randomly assigned to either the exergam…

Researchers are interviewing people who have had total knee replacement surgery to learn how they experienced the information they received during recovery. The study includes 16 men and women of all ages who are rehabilitating in primary care after their operation. Using guided …

This study looked at two different heart stents (tiny mesh tubes used to open blocked arteries) to see which one works better in routine hospital care. Over 1,000 patients who needed a stent took part. The goal was to compare costs, procedure time, and how many extra devices were…

This study follows 87 women who had chronic low back pain 13 years ago to see how their pain, daily activities, and ability to work have changed. Researchers are looking for patterns that might predict who will improve or worsen over time. The goal is to better understand the lon…

This study followed 113 people with cystic fibrosis (CF) over two years to see how many developed antibodies against COVID-19, either from infection or vaccination. Researchers collected blood samples and health data to understand if CF patients have a lower infection rate and ho…

This study looked at whether a device called the GNRB arthrometer can reliably measure knee looseness (laxity) in people with an ACL tear, both before and after reconstructive surgery. Seventeen adults with a first-time ACL injury were tested by two examiners using the GNRB and a…

This large observational study followed over 288,000 people with hip or knee osteoarthritis who received core treatment (education, exercise, and weight loss advice). The goal was to identify factors like socioeconomic status and other health conditions that predict long-term out…