New course aims to lift brain fog in Graves' patients
NCT ID NCT06134219
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether a special course on mental fatigue can help people with Graves' disease who struggle with ongoing brain tiredness, trouble focusing, and memory issues. About 96 adults aged 18-72 with stable thyroid levels will either take the course plus standard care or receive standard care alone. Researchers will check if the course reduces mental fatigue and improves quality of life over 12 months.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 96 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Oct 2023
- Expected to finish
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May 2027
An estimate. End dates often move.
- Lead sponsor
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A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 72 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * 18-72 years old * 15-72 months since first Graves' diagnosis * high free thyroxin and thyroid antibodies (TRAb) at diagnosis * euthyroid the last 6 months normal thyroid hormone levels at inclusion * symptoms on MF in connection to Graves diagnosis * MF-scale ≥10.5 points Exclusion criteria: * other diseases or situations that may be associated with mental fatigue (such as other active inflammatory disease, neurological disease) * pregnancy * lactation * assessment that the patient cannot follow the study protocol.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Agneta Lindo
RECRUITINGGothenburg, 413 45, Sweden
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Two autoimmune conditions, one child: study probes hidden thyroid trouble
- Eye damage in Graves' disease: can early clues predict who is at risk?
- Why does Graves' disease leave some brains exhausted? scientists hunt for clues in blood and spinal fluid
- Hidden thyroid cancers may be more common in Graves' disease than thought
- Can a steroid shot make thyroid surgery safer?
- Targeting the immune system: a new antibody may free Graves' patients from daily drugs