University Of California, San Francisco

This study tested three different blood pressure medications and three different home monitoring approaches for young adults (ages 18-40) with high blood pressure. The goal was to see which combinations worked best to control blood pressure while also looking at quality of life a…

This study tested whether giving a drug called pembrolizumab, with or without another drug called axitinib, before and after surgery could help people with advanced kidney cancer. The goal was to see if this approach could better control the cancer and reduce the chance of it com…

This study tested a device called Nanodropper that makes eye drops smaller. Researchers wanted to see if using these smaller drops was just as good at lowering eye pressure as using regular-sized drops from the standard bottle. The trial involved 16 adults with stable glaucoma or…

This study aimed to find the best way to treat a painful and potentially blinding eye infection called cytomegalovirus (CMV) anterior uveitis. It compared an oral antiviral pill (valganciclovir) against an antiviral eye drop (ganciclovir 2%) and a placebo in 51 adults with a conf…

This study tested 11 different low-cost text and video messages to see which ones best encourage adults at higher risk for HIV in rural Kenya and Uganda to get tested again. The goal is to find the most effective ways to promote regular testing, which helps find new infections ea…

This study tested whether applying a topical drug called tranexamic acid (TXA) directly to the surgical site during breast reconstruction could reduce common complications like bleeding (hematoma) and fluid collection (seroma). Each participant acted as their own control, with on…

This study tested whether a drug called n-acetylcysteine (NAC), which breaks down mucus, could improve lung function in adults with moderate-to-severe asthma. Participants had evidence of mucus plugs in their lungs seen on CT scans. In this small, terminated trial, adults receive…

This small pilot study tested whether improving sleep patterns could help people with mild cognitive impairment or early Alzheimer's disease. Researchers developed a non-drug program combining bright light therapy and behavioral techniques to regulate daytime and nighttime sleep.…

This study tested if adding blood flow restriction training to standard physical therapy helps people recover better after knee cartilage (meniscus) repair surgery. It compared two groups of patients: one using a special cuff during exercises and one using a regular cuff. The mai…

This study looked at whether people find it acceptable to use a medication called misoprostol to restart a late period, without first taking a pregnancy test. Researchers enrolled 17 people who had a period that was up to two weeks late and did not want to be pregnant. The goal w…

This study aimed to understand how exposure to chemicals from everyday products and pollution during pregnancy might affect future cancer risks for both mothers and their children. Researchers planned to follow over 1,500 pregnant women and their kids for several years, collectin…

This study aimed to discover new causes of severe asthma attacks and better understand how common steroid inhalers work. Researchers analyzed mucus and saliva from 67 adults during a serious asthma episode. The goal was to find clues that could lead to new treatments by studying …