University Of California, San Francisco
Clinical trials sponsored by University Of California, San Francisco, explained in plain language.
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Eye infection breakthrough? new study tests antiviral drops vs pills
Disease control TerminatedThis study compared oral valganciclovir, topical ganciclovir 2%, and placebo for treating CMV anterior uveitis, a viral eye infection that can cause pain, glaucoma, and vision loss. The trial enrolled 51 participants with PCR-confirmed CMV in the eye. The goal was to see which tr…
Phase: PHASE2, PHASE3 • Sponsor: University of California, San Francisco • Aim: Disease control
Last updated May 26, 2026 02:59 UTC
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Young adult blood pressure study tests new monitoring methods
Disease control TerminatedThis pilot study looked at how well three different blood pressure medicines and three ways of tracking blood pressure at home work in young adults aged 18 to 40 with high blood pressure. The goal was to see which approach helps lower blood pressure best and improves quality of l…
Phase: PHASE2 • Sponsor: University of California, San Francisco • Aim: Disease control
Last updated May 26, 2026 02:51 UTC
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Immune booster before kidney surgery shows promise but study halted
Disease control TerminatedThis study looked at giving the immunotherapy drug pembrolizumab (with or without axitinib) to people with advanced kidney cancer before they had surgery to remove the tumor. The goal was to see if this approach could increase immune cells in the tumor and help control the cancer…
Phase: PHASE2 • Sponsor: University of California, San Francisco • Aim: Disease control
Last updated May 22, 2026 13:55 UTC
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Failed sarcoidosis study sought blood test to predict drug success
Symptom relief TerminatedThis study tested whether Acthar gel can improve symptoms and lung function in people with sarcoidosis, a disease that causes inflammation in the lungs. Researchers also checked if a blood marker called CXCL9 could predict who would benefit. Only 2 people enrolled before the stud…
Phase: PHASE4 • Sponsor: University of California, San Francisco • Aim: Symptom relief
Last updated May 26, 2026 02:56 UTC
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Tiny drops, big hope: new device could change glaucoma treatment
Symptom relief TerminatedThis study tested a device called Nanodropper that makes smaller eye drops for people with glaucoma or high eye pressure. The goal was to see if these smaller drops lower eye pressure just as well as standard drops. The study planned to include 16 adults who already use a common …
Phase: NA • Sponsor: University of California, San Francisco • Aim: Symptom relief
Last updated May 26, 2026 02:48 UTC
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Asthma mucus study fizzles: NAC mist trial halted early
Symptom relief TerminatedThis study tested a 20% n-acetylcysteine (NAC) mist to help clear mucus in people with moderate-to-severe asthma. Participants received either NAC or a placebo for two weeks, then switched. The trial was stopped early after enrolling only 4 people, so no clear conclusions can be …
Phase: PHASE4 • Sponsor: University of California, San Francisco • Aim: Symptom relief
Last updated May 20, 2026 11:57 UTC
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Missed period pill study: a new option for menstrual regulation?
Symptom relief TerminatedThis study explored whether people would accept using misoprostol alone to bring on a late period, without first confirming pregnancy. It involved 17 adults whose periods were up to 14 days late. Researchers measured interest and satisfaction with this approach, as well as how we…
Phase: PHASE4 • Sponsor: University of California, San Francisco • Aim: Symptom relief
Last updated May 20, 2026 11:57 UTC
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Blood flow training may boost knee recovery after meniscus surgery
Symptom relief TerminatedThis study looked at whether blood flow restriction training (using a cuff to limit blood flow during exercise) helps people regain knee strength and muscle size after meniscus repair surgery. About 15 participants were planned, comparing this method to standard rehab. The study …
Phase: NA • Sponsor: University of California, San Francisco • Aim: Symptom relief
Last updated May 20, 2026 11:56 UTC
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Can a simple drug stop Post-Surgery bleeding in breast cancer patients?
Symptom relief TerminatedThis study tested whether applying tranexamic acid (TXA) directly to the surgical area during breast removal and reconstruction reduces bleeding and fluid collections. It involved 23 women at high risk for or with breast cancer. The goal was to improve recovery and lower the chan…
Phase: PHASE4 • Sponsor: University of California, San Francisco • Aim: Symptom relief
Last updated May 20, 2026 11:54 UTC
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Blood test may predict memory loss in prostate cancer treatment
Knowledge-focused TerminatedThis study aimed to see if a simple blood test could predict which men with prostate cancer might experience memory or thinking problems from hormone therapy (ADT). Researchers planned to follow 32 men over time, comparing those on ADT to those not on it. The study was terminated…
Sponsor: University of California, San Francisco • Aim: Knowledge-focused
Last updated May 26, 2026 03:04 UTC
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Pregnancy pollution link? study probes cancer risks from everyday chemicals
Knowledge-focused TerminatedThis study looked at how chemicals in everyday products and the environment might affect cancer risk in pregnant women and their children. Researchers measured levels of pollutants like PFAS, phthalates, and pesticides in 1,576 participants. The goal was to understand if pregnanc…
Sponsor: University of California, San Francisco • Aim: Knowledge-focused
Last updated May 26, 2026 03:03 UTC
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Scientists probe hidden causes of asthma Flare-Ups
Knowledge-focused TerminatedThis study looked at what causes sudden, severe asthma attacks in adults aged 18 to 75. Researchers measured the thickness and stickiness of mucus from patients having an asthma attack to better understand the disease and how inhaled steroids work. The goal was to find new ways t…
Sponsor: University of California, San Francisco • Aim: Knowledge-focused
Last updated May 26, 2026 02:57 UTC
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Light therapy and sleep coaching aim to slow memory loss
Knowledge-focused TerminatedThis small study tested a non-drug program to improve sleep and thinking in older adults with mild memory problems or early Alzheimer's. The program combined bright light therapy and a special type of sleep coaching. The goal was to see if the approach was practical and could hel…
Phase: NA • Sponsor: University of California, San Francisco • Aim: Knowledge-focused
Last updated May 26, 2026 02:53 UTC
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Can cheap text messages boost HIV retesting? pilot study aims to find out
Knowledge-focused TerminatedThis pilot study tested several low-cost behavioral nudges, like videos and text messages, to encourage HIV retesting in adults at higher risk in rural Kenya and Uganda. The goal was to see which approaches were acceptable and feasible, not to directly improve health. The results…
Phase: NA • Sponsor: University of California, San Francisco • Aim: Knowledge-focused
Last updated May 26, 2026 02:51 UTC