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Kidney cancer drug combo tested before surgery – study halted early

NCT ID NCT04370509

First seen Nov 06, 2025 · Last updated Jun 17, 2026 · Updated 26 times

Summary

This study looked at whether giving the immunotherapy drug pembrolizumab (with or without axitinib) before surgery could help control advanced kidney cancer. Only 6 people took part before the study was stopped early. The goal was to see if the treatment boosted immune cells in the tumor and shrank the cancer, but results are limited due to the small number of participants.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • University of California, San Francisco

    San Francisco, California, 94143, United States

Conditions

The condition(s) this trial relates to.

clear cell renal carcinoma Clear-cell metastatic renal cell carcinoma nonpapillary renal cell carcinoma renal cell adenocarcinoma renal cell carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.