New drug combo shows promise in shrinking kidney tumors before surgery
NCT ID NCT04370509
First seen Nov 06, 2025 · Last updated Jun 13, 2026 · Updated 25 times
Summary
This study tested whether giving pembrolizumab (an immunotherapy) with or without axitinib (a targeted drug) before surgery helps control advanced kidney cancer. Six participants with clear cell kidney cancer that had spread were enrolled. The goal was to see if the treatment boosts immune cells in tumors and reduces cancer growth before surgery. The study was terminated early, so results are limited.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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University of California, San Francisco
San Francisco, California, 94143, United States
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