Tiny drops, big hope? study tests nanodropper for glaucoma
NCT ID NCT05273385
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether a device called Nanodropper, which makes smaller eye drops, works as well as standard eye drops for lowering eye pressure in people with glaucoma or ocular hypertension. The study enrolled 16 adults who already used a common glaucoma drop. The goal was to see if the smaller drops could control eye pressure just as effectively, potentially reducing waste and side effects.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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16 people
The number who actually took part.
- Started
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Oct 2022
- Finished
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Dec 2024
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. 18 years old or older 2. Diagnosis of open-angle glaucoma (OAG) or ocular hypertension (OHT) 3. Use of prostaglandin analogue (PGA) eye drop 4. Stable disease status (no visual field loss progression or increase in IOP-lowering medications in the last 6 months) Exclusion Criteria: 1. Uncontrolled glaucoma 2. Have had eye surgery (including laser procedures) within the past six months 3. Have a diagnosis of acute angle-closure glaucoma and/or other retinal diseases 4. Use of non-PGA class of IOP-lowering medication
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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University of California, San Francisco
San Francisco, California, 94143, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can exercise shield the eyes of glaucoma patients?
- The 20-Minute squeeze: how eye injections push pressure up
- Can better Follow-Up schedules save sight in glaucoma?
- Portable devices could take the guesswork out of eye pressure checks
- Eye drops may shield the cornea after cataract surgery
- Can a puff of air replace the eye pressure probe?