The University Of Texas Health Science Center, Houston
Clinical trials sponsored by The University Of Texas Health Science Center, Houston, explained in plain language.
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Which pill works best for postpartum high blood pressure?
Disease control CompletedThis study tested two common blood pressure pills in 70 new mothers with high blood pressure after childbirth. One pill combines a water pill with a vessel relaxer; the other is a calcium blocker. The goal was to see which one controls blood pressure better in the first week afte…
Phase: PHASE4 • Sponsor: The University of Texas Health Science Center, Houston • Aim: Disease control
Last updated May 01, 2026 15:59 UTC
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Light therapy shows promise for treating gum disease
Disease control CompletedThis study tested whether adding a light-activated antimicrobial treatment to standard deep cleaning improves gum disease outcomes. Twenty adults with at least one deep gum pocket on each side of the mouth received standard cleaning on one side and cleaning plus the light treatme…
Phase: NA • Sponsor: The University of Texas Health Science Center, Houston • Aim: Disease control
Last updated Apr 30, 2026 15:51 UTC
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Could a diabetes drug help people stay off cocaine?
Disease control CompletedThis study looked at whether pioglitazone, a diabetes medicine, combined with cognitive behavioral therapy can help people who recently stopped using cocaine stay drug-free. 61 adults with cocaine use disorder took part. The goal was to see if the drug improves brain health and r…
Phase: PHASE2 • Sponsor: The University of Texas Health Science Center, Houston • Aim: Disease control
Last updated Apr 29, 2026 15:14 UTC
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Quick test could save newborns from syphilis and HIV in guatemala
Diagnosis CompletedThis study tested a fast, simple blood test that checks for both syphilis and HIV at the same time in pregnant women in Guatemala. The goal was to see if using this test would help more women get screened and treated during pregnancy, reducing the chance of passing these infectio…
Phase: NA • Sponsor: The University of Texas Health Science Center, Houston • Aim: Diagnosis
Last updated Apr 29, 2026 15:04 UTC
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Free healthy food helps at-risk americans avoid diabetes
Prevention CompletedThis study tested a program that gives free healthy food to people at risk for diabetes. The goal was to help them stick with a diabetes prevention plan and make lasting changes to their diet and lifestyle. 61 adults with high blood sugar took part. Researchers tracked how many c…
Phase: NA • Sponsor: The University of Texas Health Science Center, Houston • Aim: Prevention
Last updated Apr 29, 2026 15:05 UTC
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Can a classroom program keep kids off vapes? new study puts it to the test
Prevention CompletedThis study tested a program called CATCH My Breath to see if it could delay or prevent e-cigarette use in middle school students. About 2,000 students from 20 schools took part, with some schools using the program and others using standard tobacco prevention lessons. Researchers …
Phase: NA • Sponsor: The University of Texas Health Science Center, Houston • Aim: Prevention
Last updated Apr 29, 2026 15:05 UTC
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New hope for mystery diarrhea: drug shows promise in pilot study
Symptom relief CompletedThis study looked at whether the drug crofelemer can help people with chronic diarrhea that has no clear cause. It involved 93 adults who had frequent loose stools for at least 4 weeks. Researchers also checked which medical tests are best for finding treatable causes of the diar…
Phase: PHASE4 • Sponsor: The University of Texas Health Science Center, Houston • Aim: Symptom relief
Last updated May 01, 2026 17:42 UTC
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Robotic suit boosts heart rate and walking in spinal injury patients
Symptom relief CompletedThis study looked at whether people with spinal cord injuries can safely reach a high heart rate while walking in a wearable robotic exoskeleton. Eleven participants completed five training sessions using the Ekso exoskeleton. Researchers measured heart rate and walking speed to …
Phase: NA • Sponsor: The University of Texas Health Science Center, Houston • Aim: Symptom relief
Last updated May 01, 2026 17:42 UTC
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Could a Head-Zap at home calm Alzheimer's agitation?
Symptom relief CompletedThis small study tested whether a home-based brain stimulation technique called tDCS is safe and acceptable for people with Alzheimer's disease who have behavioral symptoms like agitation or apathy. Only 3 participants took part, and the main goal was to see if they and their car…
Phase: NA • Sponsor: The University of Texas Health Science Center, Houston • Aim: Symptom relief
Last updated May 01, 2026 17:42 UTC
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Simple leg lift may prevent dangerous blood pressure drop during surgery
Symptom relief CompletedThis study tested whether raising a patient's legs during the start of general anesthesia can prevent a sudden drop in blood pressure. Researchers studied 200 adults having surgery. They compared those who had their legs elevated to those who did not, and measured how many experi…
Phase: NA • Sponsor: The University of Texas Health Science Center, Houston • Aim: Symptom relief
Last updated May 01, 2026 16:00 UTC
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New tissue graft takes on frozen shoulder in Head-to-Head trial
Symptom relief CompletedThis study tested whether a special tissue graft called ActiveMatrix works better than the usual steroid injection for frozen shoulder. Fifty-six adults with frozen shoulder received either the graft or a steroid shot, and researchers tracked their pain and shoulder function for …
Phase: PHASE4 • Sponsor: The University of Texas Health Science Center, Houston • Aim: Symptom relief
Last updated May 01, 2026 15:58 UTC
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Skin glue showdown: which one causes fewer rashes?
Symptom relief CompletedThis study tested two different skin glues used to close small cuts from laparoscopic or robotic belly surgery. 180 adults took part to see which glue caused less skin rash or redness. The goal is to find the gentler option for patients.
Phase: PHASE3 • Sponsor: The University of Texas Health Science Center, Houston • Aim: Symptom relief
Last updated Apr 29, 2026 15:04 UTC
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Diabetes drug shows promise for quitting smoking without weight gain
Symptom relief CompletedThis study tested whether exenatide, a drug used for diabetes, can help people quit smoking and prevent the weight gain that often happens after quitting. 140 smokers who wanted to quit used a nicotine patch and either exenatide or a placebo. The goal was to see if exenatide impr…
Phase: PHASE2 • Sponsor: The University of Texas Health Science Center, Houston • Aim: Symptom relief
Last updated Apr 29, 2026 15:01 UTC
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Sleep aid shows promise in curbing smoking cravings
Symptom relief CompletedThis study tested whether suvorexant, a drug used for sleep, could help reduce smoking cravings and stress in people who smoke. Fourteen non-treatment-seeking smokers took part in a double-blind, placebo-controlled trial. Researchers measured cravings, stress, and smoking behavio…
Phase: PHASE2 • Sponsor: The University of Texas Health Science Center, Houston • Aim: Symptom relief
Last updated Apr 28, 2026 13:02 UTC
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Which anesthesia is better for stroke patients? new study investigates
Symptom relief CompletedThis study looked at 260 stroke patients to see if being awake with sedation or fully asleep under general anesthesia leads to better recovery after a procedure to remove a clot. The goal was to find out which approach reduces disability three months later. Results help doctors c…
Phase: PHASE4 • Sponsor: The University of Texas Health Science Center, Houston • Aim: Symptom relief
Last updated Apr 26, 2026 20:02 UTC
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Can a fatty acid lift bipolar depression? small trial tests PEA
Symptom relief CompletedThis study tested whether a natural fatty acid compound called palmitoylethanolamide (PEA) can help reduce depression in people with bipolar disorder. Thirty-four adults who were already taking a mood stabilizer took part. Researchers measured changes in depression scores and loo…
Phase: PHASE2 • Sponsor: The University of Texas Health Science Center, Houston • Aim: Symptom relief
Last updated Apr 26, 2026 20:01 UTC
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New program aims to close COVID-19 testing gaps in vulnerable communities
Knowledge-focused CompletedThis study tested a program that used community health workers and text messages to encourage COVID-19 testing and vaccination in underserved areas. 384 adults with smartphones took part. The goal was to see if this approach could increase testing and vaccination rates, and if su…
Phase: NA • Sponsor: The University of Texas Health Science Center, Houston • Aim: Knowledge-focused
Last updated Apr 30, 2026 15:50 UTC
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803 NDPH patients share their headache stories in landmark survey
Knowledge-focused CompletedThis study surveyed 803 people diagnosed with New Daily Persistent Headache (NDPH) to learn about their headache patterns and what treatments they have tried. Participants completed an online questionnaire about their symptoms and experiences. The goal was to gather information t…
Sponsor: The University of Texas Health Science Center, Houston • Aim: Knowledge-focused
Last updated Apr 30, 2026 15:50 UTC
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Thousands of cluster headache patients share what works for them
Knowledge-focused CompletedThis study surveyed nearly 2,500 people with cluster headaches to learn which treatments they find most effective and what they think about new options. Participants filled out one online questionnaire. The goal was to gather patient insights, not to test a new treatment.
Sponsor: The University of Texas Health Science Center, Houston • Aim: Knowledge-focused
Last updated Apr 29, 2026 15:03 UTC
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Which sterilization route is best? new study asks patients
Knowledge-focused CompletedThis study looked at how women felt after having their tubes tied (sterilization) using one of three different surgical methods. Researchers asked 255 women about their recovery, satisfaction, and body image after surgery. The goal was to find out which approach gives the best pa…
Phase: NA • Sponsor: The University of Texas Health Science Center, Houston • Aim: Knowledge-focused
Last updated Apr 26, 2026 20:01 UTC