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Could a fatty acid ease bipolar depression?

NCT ID NCT06229977

First seen Nov 01, 2025 · Last updated May 24, 2026 · Updated 28 times

Summary

This study tested whether a natural compound called palmitoylethanolamide (PEA) can help reduce depression in people with bipolar disorder. 34 adults who were already taking a mood stabilizer took PEA or a placebo. Researchers measured changes in depression scores and looked for links to the body's own cannabinoid and immune signals.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • The University of Texas Health Science Center at Houston

    Houston, Texas, 77030, United States

Conditions

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