The University Of Texas Health Science Center, Houston

This study tracks 100 people with pancreatic cysts or tumors who receive a treatment called endoscopic ultrasound-guided radiofrequency ablation (EUS-RFA). A thin needle delivers heat directly to the lesion to destroy it. Researchers will monitor how well the procedure works and …

This study tests whether a comprehensive program of lifestyle changes (diet, exercise, education) plus aggressive cholesterol-lowering drugs, guided by PET heart scans, can reduce heart attacks and deaths better than standard medical care. Over 1,000 adults with suspected or know…

This study tests a program called HEROES that combines medication (Suboxone), counseling, and community outreach to help people with opioid use disorder engage and stay in treatment. Researchers will enroll 3,000 participants in Houston to see if this approach improves treatment …

This pilot study aimed to test a new, more targeted ablation technique for atrial fibrillation using advanced mapping technology. The goal was to see if it could shorten procedure time and reduce the number of burns needed compared to the standard approach. However, the study was…

This study planned to test a device called RetroPerc that helps doctors reach and remove large kidney stones. It was designed for adults with kidney stones larger than 10 mm. However, the study was withdrawn before any participants were enrolled, so no results are available.

This study looks at whether giving a higher dose of vitamin D (800 IU daily) to extremely premature infants (born before 28 weeks or weighing under 1000 grams) can improve their health. Researchers will check vitamin D levels and measure effects on the lungs, bones, immune system…

This study tests a video-based telehealth program for stroke survivors. After leaving the hospital, participants get an iPad and a blood pressure monitor, plus telehealth visits with a nurse and social worker. The goal is to see if this program helps more people keep their blood …

This study tests a patch made from donated human umbilical cord tissue to repair spina bifida while the baby is still in the womb. Surgeons use a tiny camera to place the patch over the spinal opening, aiming to protect the nerves and reduce problems after birth. The trial includ…

This study tests whether giving extremely preterm babies less intravenous (IV) fat (lipids) can lower harmful bilirubin levels and protect their brain development. Bilirubin can build up in these tiny infants and cause hearing loss or long-term disabilities. Researchers will comp…

This study tests a brain pacemaker (deep brain stimulation) for people with severe depression that hasn't improved with other treatments. About 16 adults aged 22-70 will receive the implant, which sends electrical pulses to a specific brain area. The goal is to safely reduce depr…

This study tests a lifestyle program called Healthy Liver/Hígado Sano for Hispanic patients with metabolic-dysfunction associated steatotic liver disease (MASLD), also known as fatty liver disease. The program includes education sessions and family support to help participants lo…

This study looks at whether giving extra vitamin D (800 IU daily) to extremely premature infants (born before 28 weeks or weighing under 1000 grams) improves their lung, bone, immune, and brain health. About 180 babies will receive either the extra vitamin D or usual care for the…

This study uses a special camera and a safe dye to take pictures of the lymphatic system, which helps move fluid in the body. Researchers want to see how this system works in healthy people and in those with conditions like lymphedema or lipedema. The goal is to find patterns tha…

This study tests whether starting lymphatic treatment early—before any swelling appears—can prevent lymphedema in head and neck cancer survivors. Twenty adults who have completed surgery and radiation will be split into two groups: one uses a daily home compression device, the ot…

This study tests whether a high-dose, intensive arm therapy program can improve movement and quality of life in people who had a stroke at least 6 months ago. Nine participants will receive 6 hours of therapy daily (occupational, physical, and guided individual work) for 3 weeks.…

This study tests whether a mobile app, supported by a community health worker, can help stroke survivors recover at home. Eleven uninsured stroke survivors in Texas will use the app for personalized exercises and receive support. The goal is to see if this approach improves mobil…

This study tests whether pressing specific points on the ear (auricular point acupressure) can reduce pain, numbness, and tingling caused by chemotherapy. About 225 cancer patients will try this non-needle technique. Researchers will also measure changes in nerve function and bod…

This study was designed to see if low-intensity focused ultrasound could safely change brain activity related to emotion and thinking in healthy volunteers. Researchers planned to use brain scans to measure effects. However, the study was withdrawn before enrolling any participan…

This study looks at whether a pneumatic compression device can improve lymphatic function in people with leg swelling from chronic venous disease. 34 participants will be split into two groups: one gets standard compression bandages, the other adds daily pneumatic compression at …

This study planned to observe how a special, continuous-use ultrasound probe placed in the esophagus helps doctors make treatment decisions for patients with unstable blood pressure. It aimed to enroll 60 adults from trauma and heart surgery units. However, the study was withdraw…

This large observational study is collecting medical data and biological samples from 5,000 people with chronic spinal cord or traumatic brain injury, as well as family members and healthy volunteers. Researchers hope to build a rich database to better understand these conditions…

This study aimed to see if giving antibiotics to pregnant people whose water broke very early (before 22 weeks) could delay delivery and improve baby health. It was planned for those with a single baby and recent membrane rupture. However, the study was withdrawn before enrolling…

This study looks at how headaches work by using capsaicin (the spicy part of chili peppers) and ice water to trigger mild, temporary pain in people with and without headache disorders. Researchers measure changes in pain signals and tear production to better understand conditions…

This study aimed to see if having clear liquids up to one hour before gallbladder surgery is as safe as the standard overnight fast. It planned to measure stomach contents, patient comfort, and surgery scheduling. However, the study was withdrawn before enrolling any participants…

This study follows 1,500 young people over time to learn what factors—like personal attitudes, relationships, and neighborhood—lead to gun access, carrying, or use. It also includes in-depth interviews with known gun carriers. The goal is to identify risks and protective factors …

This study looks at how the brain learns to be afraid and how it learns to avoid things. About 150 healthy adults will look at pictures on a screen and sometimes get a mild shock. By measuring brain waves and sweat, researchers hope to understand the brain circuits involved in fe…

This study looks at what to do when a surgeon finds a small, hidden groin hernia during a routine hernia repair. It compares fixing it right away versus just watching it over time. The goal is to help patients and doctors decide the best approach by creating a simple decision-mak…

This study tests an online group program designed to help people with spinal cord injury (SCI) stay healthy as they age. Researchers will enroll 180 adults who have had a traumatic SCI for at least 15 years or are over 45, and who use a wheelchair. The program focuses on improvin…

This study looks at whether a new program can help community health clinics better care for cancer survivors. Over 5,500 patients and their clinicians will take part. The goal is to see if the program increases screening for new cancers and improves how well doctors understand su…

This study tests a program that offers housing and on-site employment to adults who are at risk of homelessness. Researchers want to see if this approach reduces emergency room visits and improves housing stability, employment, and quality of life. About 750 participants will be …