The University Of Texas Health Science Center, Houston

This study tests whether adding a simple stitch to support the top of the vagina during a scarless hysterectomy (vNOTES) can help prevent pelvic organ prolapse later on. Fifty women having a vNOTES hysterectomy for non-cancer reasons will be enrolled. The surgeons will measure va…

This study tests a new, non-invasive treatment using low-intensity focused ultrasound (LIFU) to help people quit smoking. It targets deep brain areas linked to nicotine addiction without surgery or needles. The study will enroll 100 adults who have smoked for at least 5 years and…

This study looks at how well a new device called GentleWave cleans out infected tissue from deep inside root canals. Researchers will examine 50 extracted human molars under a microscope to see how much pulp tissue and bacteria remain after the procedure. The goal is to improve r…

This study will test a rapid fingerstick test for HIV and syphilis in pregnant women who come to the emergency department without prior prenatal care. Researchers want to see if offering this test leads to more women being diagnosed and starting treatment right away. The goal is …

This study tests whether giving high-risk pregnant women free fresh produce can prevent gestational diabetes. Researchers will enroll 400 women receiving care at Harris Health clinics who are early in pregnancy and have risk factors like obesity. Participants will receive a "Food…

This study looks at ways to improve care for teens and young adults who have experienced sexual assault. The goal is to offer same-day HIV prevention medicine and substance use support during their emergency room visit. Researchers will work with young people to design and test t…

This pilot study tests a personalized version of stepped-care cognitive behavioral therapy for PTSD in Latino children aged 7-12. The therapy involves a caregiver-led first step with therapist support, followed by more intensive therapy if needed. The goal is to see if adapting t…

This study tests a therapy called Mentalizing Imagery Therapy (MIT) for family caregivers of people with Alzheimer's or related dementias. The goal is to see if it can lower stress, depression, and the risk of elder mistreatment. About 50 caregivers who provide at least 8 hours o…

This study will test a mobile app called ¡Iniciando! designed to help Latino young adults with autism and their families navigate the move to adulthood. The app includes virtual group sessions and coaching over three months. Researchers want to see if the app is easy to use and h…

This study tests a 16-week exercise program designed specifically for Hispanic people with multiple sclerosis who have walking problems. About 66 participants will either join the exercise group or a waitlist. The goal is to see if the program improves walking ability and quality…

This study tests a testosterone gel applied to the skin to see if it can safely improve low sexual desire and arousal in women going through or past menopause. About 150 women aged 40-65 with diagnosed low libido will receive either the gel or a placebo for several months. The go…

This study tests whether a virtual home rehabilitation program helps stroke survivors in underserved Texas communities recover better than standard care alone. About 80 adults who recently had a stroke and are returning home will take part. The program uses video sessions to guid…

This study looks at whether using a special brain monitor (BIS) can help people on breathing machines in the ICU. The monitor tracks sedation levels, which may help doctors give just the right amount of medicine. Researchers want to see if this leads to shorter time on the ventil…

This study looks at whether a procedure called microneedling radiofrequency (which uses tiny needles and heat) can improve skin and fat thickness in the face, and if adding a topical cream (poly-L-lactic acid) makes it work better. About 30 adults seeking facial rejuvenation will…

This study tests a personalized version of a proven trauma therapy for Latino children ages 7-12 with PTSD. The approach starts with a lower-intensity treatment and adds more support only if needed, making care more accessible. Researchers will measure changes in trauma symptoms …

This pilot study will test whether an artificial intelligence tool can give helpful feedback to medical residents about how they talk with patients. Sixty-four surgery residents will have their conversations with actors playing patients recorded and analyzed by a large language m…

This study looks at how the drug Fintepla changes brain blood flow and breathing in people with Dravet Syndrome, a severe form of epilepsy. Researchers will use brain scans (fMRI) to measure these changes before and after taking Fintepla. The goal is to understand how the drug mi…

This study aims to improve how schools adopt programs that prevent bullying and teen dating violence. Researchers will adapt an existing tool and test it with 25 school staff in Texas, including administrators, teachers, and counselors. The goal is to see if the tool is easy to u…

This study will test whether continuously monitoring vital signs like oxygen levels and heart rate after major surgery can reduce complications compared to standard intermittent checks. About 492 adults having non-cardiac surgery will be randomly assigned to either have their dat…

This study tests a simple screening tool to help doctors find muscle stiffness (spasticity) sooner after a stroke. Researchers will track how quickly spasticity is detected and whether the tool helps doctors make faster treatment decisions. About 80 adults who recently had a stro…

This study will test whether a virtual reality (VR) program for thinking and physical exercises is practical and easy to use for people with mild cognitive impairment (MCI) or subjective memory decline. Ten participants will try the VR activities, and researchers will measure how…

This study looks at how often people develop allergic skin reactions to two different wound dressings used after open shoulder surgery: one made from silk protein and another from a medical glue mesh. About 350 adults having shoulder surgery will be randomly assigned to one dress…

This study measures how raising or lowering the jaw (the space between upper and lower teeth) changes the shape of the lower face and lip positions. Researchers will study 50 adults who wear full dentures or overdentures. The goal is to understand these changes better, not to tes…

This study looks at whether a program called MAGIC, which adds short physical activity breaks and lessons into the school day, can help elementary students be more active and lower their risk for heart problems. Researchers will track how well teachers use the program and measure…