Can a Needle-and-Heat combo rejuvenate your face?
NCT ID NCT07261527
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at whether a procedure called microneedling radiofrequency (which uses tiny needles and heat) can improve skin and fat thickness in the face, and if adding a topical cream (poly-L-lactic acid) makes it work better. About 30 adults seeking facial rejuvenation will take part. The goal is to see if the treatment improves appearance and how satisfied patients are.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 30 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Nov 2025
An estimate. Start dates often move.
- Expected to finish
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Nov 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Seeking facial rejuvenation for cosmetic concerns * Able and willing to provide informed consent * Willing to comply with study procedures and follow-up visits Exclusion Criteria: * Prior filler injection or energy-based device treatment to the face within the past 6 months * Previous facial surgeries * Pregnant or breastfeeding * Active infection, dermatitis, or open lesions in the treatment area * History of keloids or abnormal scarring * Known allergy to poly-L-lactic acid (PLLA)- Current participation in another clinical trial involving facial aesthetic treatments * Presence of pre-cancerous or cancerous lesions in the treatment area * Current or planned use of glucagon-like peptide-1 receptor agonists (e.g., Ozempic, semaglutide) during the study period. Subjects on these medications will be excluded due to potential effects on facial fat and overall weight. * HIV+ patients * Patients on HIV medications- Patients that have eczema and rosacea
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Genom att skicka in godkänner du våra Användarvillkor
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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The University of Texas Health Science Center at Houston
Houston, Texas, 77030, United States
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