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Collagen pills may boost skin firmness and reduce wrinkles

NCT ID NCT06755892

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether taking collagen supplements daily for 16 weeks can improve skin density, reduce wrinkles, and enhance skin texture in healthy women aged 40 to 65. Participants took either a placebo or one of four collagen-based supplements. The goal was to see if these supplements make skin look and feel younger.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

139 people

The number who actually took part.

Started

Jan 2025

Finished

Jun 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

40 to 65 years

Sex

Female participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion criteria: * Caucasian female volunteers aged between 40 and 65 years at the time of the signature of Informed consent form (ICF), * Signed Informed consent form (ICF), * Fitzpatrick skin phototypes I-IV, * Signs of skin aging, * In good general health condition, * BMI \< 35 * Willingness to avoid a consumption of any food supplements containing methylsulfonylmethane (MSM), antioxidants, collagen and other protein-based food supplements during the study, * Willingness to follow all study procedures and keeping a diary during the study (to follow their compliance and palatability). * Willingness to maintain their living habits and to not begin or change any oestrogen or progesterone therapies, * Willingness to avoid shaving/depilation of their arms during the study, * Willingness not to change cosmetic treatment routine during the study, * Willingness to avoid rejuvenation treatments during the study. Exclusion criteria: * Pregnancy or breastfeeding, * Known or suspected allergy to any ingredient of the tested products, * Changes in dietary habits and dietary supplementation in the last three months prior to inclusion, * Regular use of food supplements containing MSM, antioxidants, collagen or other protein-based food supplements in the last three months prior to inclusion, * Veganism, * Changes in cosmetic facial and body care routine in the last month prior to inclusion, * Diagnosed and uncontrolled/untreated/unregulated disease, * Any clinically significant history of serious metabolic disease, digestive tract disease, liver disease, kidney disease, haematological disease, * Intake of drugs with any impact on skin reactions (e.g., glucocorticoids, antihistamines, and immunomodulators), * Any clinically significant acute or chronic skin diseases, * Skin pigmentation disorders on measuring sites, * Anticipated sunbathing or solarium visits before or during the study, * Invasive rejuvenation treatments (e.g. needle rollers, needle mesotherapy, deep/medium-deep chemical peels, laser therapy etc.) in the last 4 months prior to study entry, * Non-invasive rejuvenation treatments (e.g. radiofrequency, electrotherapy, ultrasound, IPL therapy) in the last month prior to study entry, * Shaving/depilation of the arms in the last 14 days before inclusion, * Mental incapacity that precludes adequate understanding or cooperation.

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Conditions

The condition(s) this trial relates to.

Erythema

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • VIST - Faculty of Applied Sciences, Institute of Cosmetics

    Ljubljana, 1000, Slovenia

More trials for these conditions

Other studies related to the condition(s) this trial covers.