The Cleveland Clinic

This study tested a 24-week program that combines WeightWatchers behavioral support with medical weight management (including prescription drugs like Wegovy or Mounjaro). 180 adults with obesity or overweight plus related conditions took part. The goal was to see how much weight …

This study followed 30 people with uveitis, an eye inflammation condition, who received a fluocinolone acetonide implant. Researchers used special eye scans to measure inflammation changes over 12 months. The goal was to see how the implant affects inflammation and vision.

This study tested whether a continuous glucose monitor (CGM) can help track blood sugar changes in 20 adults with type 2 diabetes after a kidney transplant. Participants wore a small sensor that measured glucose levels around the clock. The goal was to see how often blood sugar s…

This study compared two types of surgical mesh used to repair vaginal vault prolapse, a condition where the top of the vagina drops down. 106 women having laparoscopic or robotic surgery received either Restorelle® Y mesh or Vertessa® Lite Y mesh. The main goal was to see if one …

This study compared two types of surgery for removing kidney stones: standard PCNL and a smaller version called mini-PCNL. The goal was to see which one causes less blood loss and has fewer complications. 18 adults with kidney stones took part, and researchers measured things lik…

This study tested whether the aldosterone renin ratio (ARR) blood test can help doctors find more cases of primary aldosteronism (PA), a common and often missed cause of high blood pressure that can be cured with surgery or managed with specific medications. Researchers looked at…

This study tested whether radiofrequency microneedling can safely treat melasma, a common skin condition causing dark patches, in people with darker skin (Fitzpatrick types IV-VI). Ten adults completed the treatment at Cleveland Clinic. Researchers measured changes in melasma sev…

This study tested whether a non-opioid painkiller (ketorolac) works as well as an opioid (oxycodone) for pain after kidney stone surgery. 81 adults who had a ureteroscopy and received a ureteral stent took part. For five days after surgery, they recorded pain scores, how many pil…

This study tested whether combining a gentle, non-invasive brain stimulation technique with arm exercises could help people with cervical spinal cord injury regain strength and function in their upper limbs. 47 participants completed 15 training sessions over several weeks. The g…

This study tested a group-based program to help people with moderate-to-severe sleep apnea use their Positive Airway Pressure (PAP) machine more often. 56 adults who were not using their machine enough took part. The program aimed to improve machine use, sleepiness, mood, and qua…

This small study tested whether an 8-week yoga program could help African American adults with high blood pressure lower their blood pressure, reduce stress, and improve memory for taking medications. Eight participants attended weekly yoga classes at a hospital. The study measur…

This study tested whether injecting a long-lasting numbing medicine near the chest muscles (PECS/SAP blocks) can reduce pain after minimally invasive heart surgery. 210 adults having robot-assisted mitral valve repair took part. The main goal was to see if the blocks improved a c…

This study looked at whether adding Reiki (light touch energy therapy) and manual therapy (gentle massage) to usual care helps people after their first open-heart surgery. 272 adults were randomly assigned to receive either 20 minutes of these therapies for three days after surge…

This study tested a cooling spray (vapocoolant) to see if it reduces pain when getting an IV in the emergency department. 300 adults who needed an IV were randomly given either the cooling spray or sterile water before the needle. The main goal was to measure pain scores on a 0-1…

This small study looked at whether acupuncture could improve heart function and quality of life in 14 people with chronic heart failure. Participants received acupuncture treatments over 5 weeks. Researchers measured changes in heart pumping ability, walking distance, and symptom…

This study followed 37 people with a genetic risk for hereditary ATTR amyloidosis over five years. Researchers measured a specific misfolded protein in the blood to see if it could signal when the disease starts or worsens. No treatments were tested; the goal was simply to learn …

This study looked at how a single session of exercise changes brain activity in people with Parkinson's disease who have a brain implant (DBS). Twenty-five participants completed thinking and movement tests before and after exercise. The goal was to find brain signals linked to b…

This study looked at whether stopping certain diabetes medications (incretin-based therapies) before an upper endoscopy reduces the amount of food or liquid left in the stomach. Having too much stomach content can make the procedure harder or riskier. The study included 69 adults…

This study tested how much heat people lose when covered with different types of full-body warming blankets and devices. Twenty healthy adults took part, and researchers measured heat loss at 15 spots on the body. The goal was to see which blanket-and-device combination keeps peo…

This study looked at whether using a continuous monitoring system (GE Portrait) with nurse alerts can reduce dangerous changes in vital signs like low oxygen or abnormal heart rate in patients recovering from major surgery. 227 adults who had major noncardiac surgery took part. T…

This study looked at two different heart mapping systems, RHYTHMIA and CARTO, used during repeat ablation procedures for atrial fibrillation (a type of irregular heartbeat). The goal was to see which system could better find gaps from previous treatments and help prevent the cond…

This study looked at 70 babies in the NICU to see if certain proteins called neurotrophins in their blood could predict future lung and brain development problems. Researchers measured these proteins and tracked the babies' breathing and developmental milestones. The goal was to …

This early study tested whether a 3D holographic system could help guide doctors during a procedure to repair an abdominal aortic aneurysm (a bulging blood vessel). Two patients participated, and the main goal was to see if the holographic guidance worked safely alongside standar…

This study used virtual reality to create situations that cause freezing of gait in people with Parkinson's disease who have a deep brain stimulator (DBS). While walking in VR, brain signals were recorded from the DBS device to understand what happens in the brain during freezing…

This study tested whether people with a higher body mass index (BMI) and a higher risk for sleep apnea are more likely to have breathing or heart problems during an endoscopy or colonoscopy. Researchers used two simple questionnaires (STOP-BANG and Epworth Sleepiness Scale) to sc…

This study looked at side effects of the pain medicine oliceridine in adults after major surgery. About 200 people took part. Researchers measured breathing problems and other complications to better understand the drug's safety.

This study looked at how pain in one knee changes the way people walk, especially the forces on the other knee. Researchers studied 55 adults with knee osteoarthritis and healthy volunteers. Participants walked on a treadmill and received knee injections to help measure joint loa…

This study observed how doctors discuss noninvasive prenatal testing (NIPT) with pregnant women during their first visit. The goal was to learn how to better support women in making informed decisions about this screening. About 691 pregnant women participated, and researchers me…

This study looked at how choline from eggs compares to choline from supplements in affecting TMAO, a compound in the blood linked to higher heart disease risk. About 86 adults participated, and researchers measured TMAO levels and platelet function over 28 days. The goal was to s…

This study tested new ways of delivering deep brain stimulation (DBS) to people with Parkinson's disease. Instead of constant stimulation, researchers tried intermittent patterns to see if they could control movement symptoms while reducing effects on thinking and memory. Sixteen…

This study checked if a stick-on thermometer called TempTraq can accurately measure body temperature in 60 ICU adults, compared to a standard catheter thermometer. Patients had their temperature taken under cold, normal, and hot conditions. The goal was to see if the patch is a r…

This study looked at what happens in the body after eating ultra-processed foods like hamburgers compared to whole foods like fresh vegetables. Researchers measured changes in blood and urine markers in 46 healthy adults. The goal was to understand how different foods affect our …

This study tested a telemedicine approach to deliver cervical cancer screening results to women in El Salvador. Over 1,100 women aged 30-59 took part, with some receiving results via mobile health technology. The goal was to see if using phones or tablets could help more women ge…

This study looked at how well the Dexcom G7 continuous glucose monitor matches standard blood sugar checks in 28 adults after heart surgery. Participants had their blood sugar measured every 1-3 hours using usual methods, and the Dexcom G7 readings were compared. The goal was to …

This study looked at 16 people having weight-loss surgery to see how raising pressure in the belly and chest affects a hormone called vasopressin and kidney function. Researchers measured pressure levels, hormone changes, and urine output at different times. The goal was to bette…

This study checked how well the Dexcom G6 continuous glucose monitor matches standard blood sugar tests in 40 adults after heart surgery. Participants wore the monitor while in the intensive care unit and regular hospital floors. The goal was to see if the device could reliably t…

This study tested whether a special imaging technique called near infrared fluorescence cholangiography (NIFC) helps surgeons see bile ducts more clearly during laparoscopic gallbladder removal compared to standard white light. 677 adults having gallbladder surgery took part. The…

This study looked at whether measuring a substance called cystatin C in the blood can help doctors spot kidney problems early in people being treated for acute heart failure. Researchers tracked 64 patients during their hospital stay. The goal was to understand how cystatin C lev…