The Cleveland Clinic

This study tested a stem cell product called Remestemcel-L for people with severe ulcerative colitis that did not get better with standard treatments. The goal was to see if injecting these cells into the colon was safe and could help patients avoid surgery or stronger drugs. Onl…

This study tested whether a team-based approach using continuous glucose monitors (CGMs) could help adults with type 1 diabetes who were hospitalized for diabetic ketoacidosis (DKA). The goal was to improve blood sugar control and reduce the chance of being readmitted to the hosp…

This study tested a new way to treat severe Crohn's colitis that hasn't responded to standard medicines. Doctors injected stem cells directly into the colon to see if it was safe and could help heal the gut. The study included 7 adults who were facing surgery as their next option…

This study compared two surgical methods for removing diseased intestine in people with Crohn's disease to see which better prevents the disease from returning. It involved 13 adults who needed surgery for Crohn's that didn't respond to medication. The trial was stopped early, so…

This study aimed to compare two common materials (Ethibond suture and vessel loop) used as draining setons for complex anal fistulas. The goal was to see which material better controls infection, lasts longer, and improves quality of life. The study was terminated early after enr…

This study aimed to measure how repairing large hernias of the belly wall changes internal pressure and tension on the muscles. Only 2 patients were enrolled before the study was stopped. The goal was to better understand the body's response to this type of surgery.

This study looked at whether weight-loss surgery can reverse a key sign of cell aging called telomere shortening. Telomeres are like protective caps on our DNA that get shorter as we age, and obesity can speed up that process. Researchers compared telomere length in people with s…

This observational study aimed to understand why some people with septic shock respond better to the drug vasopressin than others. Researchers planned to compare blood markers, heart ultrasound images, and tissue oxygen levels between responders and non-responders. Only 2 partici…