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Knee pain alters walking mechanics, study finds

NCT ID NCT05670236

Knowledge-focused Sponsor: The Cleveland Clinic Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at how pain in one knee affects the forces on the other knee during walking. Researchers measured walking patterns in 55 adults with knee osteoarthritis and healthy volunteers. The goal was to understand how the body adjusts movement to protect a painful joint, which could help improve treatments.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 4

Runs after approval, following long-term safety and how well the treatment works in everyday use.

Participants

55 people

The number who actually took part.

Started

Jan 2023

Finished

Jul 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

45 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria for Knee Osteoarthritis Arm: * At least 45 years old * Unilateral knee pain with walking that averages at least 3 out of 10 on a numeric pain rating scale * Unilateral knee stiffness that lasts less than 30 minutes after periods of inactivity * Unilateral symptoms on most days for at least the past 3 months Exclusion Criteria for Knee Osteoarthritis Arm: * History of knee replacement surgery * Opiate use within the past 3 months * Narcotic use within the past 3 months * Known medical condition that affects walking mechanics, besides knee osteoarthritis * Known medical condition that affects pain perception * Inability to walk for 30 minutes without using an assistive device * Body weight greater than 300 pounds * Known allergy to adhesives * High risk for a cardiovascular event * Currently pregnant * Anticoagulant use within the past 3 months * Intraarticular knee injection within the past 3 months * Known history of hypersensitivity to local anesthetics of the amide type * History of lower body pain or injury, besides knee osteoarthritis, within the past 6 months Inclusion Criteria for Healthy Arm: * At least 45 years old * No lower body pain or injury within the past 6 months Exclusion Criteria for Healthy Arm: * History of knee replacement surgery * Opiate use within the past 3 months * Narcotic use within the past 3 months * Known medical condition that affects walking mechanics * Known medical condition that affects pain perception * Inability to walk for 30 minutes without using an assistive device * Body weight greater than 300 pounds * Known allergy to adhesives * High risk for a cardiovascular event * Currently pregnant

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Conditions

The condition(s) this trial relates to.

osteoarthritis osteoarthritis, knee Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Osteoarthritis, knee

Contacts and locations

Locations

  • Cleveland Clinic

    Cleveland, Ohio, 44195, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.