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Scientists probe hidden link between belly pressure and kidneys

NCT ID NCT03707054

Knowledge-focused Sponsor: The Cleveland Clinic Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed study looked at how a controlled increase in belly pressure (from laparoscopic surgery) affects a hormone called vasopressin and kidney function. Researchers measured pressure, optic nerve size, and urine output in 16 patients having weight-loss surgery. The goal was to better understand how the body compensates during abdominal compartment syndrome, not to test a treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

16 people

The number who actually took part.

Started

Apr 2017

Finished

Dec 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 72 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age 18-72 * Patients meeting NIH criteria for bariatric surgery * Patients undergoing laparoscopic sleeve gastrectomy Exclusion Criteria: * • Age below 18 years * American Society of Anesthesiologist (ASA) class IV or V * Other evident/diagnosed causes of increased IAP or increased intrathoracic pressure, except for obesity * Active urinary tract infection * Previous or concomitant neurological disease * Previous or concomitant ophthalmic conditions/eye surgery * Previous or concomitant lung diseases

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Conditions

The condition(s) this trial relates to.

compartment syndrome Intra-Abdominal Hypertension intracranial hypertension

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Abdominal compartment syndrome Intracranial pressure increase

Contacts and locations

Locations

  • Cleveland Clinic Florida

    Weston, Florida, 33331, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.