Methodist Health System
Clinical trials sponsored by Methodist Health System, explained in plain language.
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New stent device aims to seal off dangerous brain bulges
Disease control CompletedThis study tested a medical device designed to treat unruptured, wide-necked brain aneurysms—weak bulges in brain arteries. Doctors used a small mesh tube (stent) to help hold tiny coils in place inside the aneurysm, aiming to block it off and prevent a future rupture. The study …
Phase: NA • Sponsor: Methodist Health System • Aim: Disease control
Last updated Apr 03, 2026 14:42 UTC
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Doctors test if less medication can prevent deadly transplant complication
Disease control CompletedThis study looked at whether giving liver transplant patients a lower dose of anti-rejection drugs could help prevent a rare but deadly complication called graft-versus-host disease (GVHD). Researchers followed 100 adult transplant recipients for a year to see if this approach re…
Sponsor: Methodist Health System • Aim: Disease control
Last updated Apr 01, 2026 14:41 UTC
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Weighty question: does dosing method affect survival in brain infection?
Disease control CompletedThis study looked back at medical records to see if the way doctors calculate acyclovir doses for obese patients with HSV encephalitis (a serious brain infection) affects survival. Researchers examined 50 patients across six hospitals to compare outcomes when doses were based on …
Sponsor: Methodist Health System • Aim: Disease control
Last updated Mar 31, 2026 12:12 UTC
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Precision radiation dosing tested for tough liver cancers
Disease control CompletedThis study tested a flexible dosing approach for delivering radiation beads (Y90 SIR-Spheres) directly to liver tumors that cannot be surgically removed. Researchers followed one patient to see if adjusting radiation doses based on individual tumor characteristics could improve t…
Sponsor: Methodist Health System • Aim: Disease control
Last updated Mar 31, 2026 12:11 UTC
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ER scorecard aims to stop dangerous drug Mix-Ups
Disease control CompletedThis study tested a new scoring tool designed to help emergency room staff identify patients at high risk for serious medication problems that could send them back to the hospital. The tool flagged patients so a pharmacist could review all their medications before they went home.…
Sponsor: Methodist Health System • Aim: Disease control
Last updated Mar 30, 2026 14:35 UTC
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New antibiotic tested for dangerous diabetic foot infections
Disease control CompletedThis study tested the safety and effectiveness of the antibiotic omadacycline for treating moderate-to-severe diabetic foot infections, sometimes with bone infection. It involved 42 hospitalized patients and compared their outcomes to past patients who received standard antibioti…
Sponsor: Methodist Health System • Aim: Disease control
Last updated Mar 30, 2026 14:35 UTC
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Doctors review surgery to unblock Life-Threatening vein in dialysis patients
Disease control CompletedThis study looked back at 45 dialysis patients who had surgery to fix a blocked major chest vein (Superior Vena Cava). The blockage causes dangerous swelling and pressure. Researchers reviewed patient records to see how well the surgery worked to relieve symptoms and keep the vei…
Sponsor: Methodist Health System • Aim: Disease control
Last updated Mar 30, 2026 14:34 UTC
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Doctors test group sessions to fight obesity
Disease control CompletedThis small study tested whether group doctor visits could help people with obesity lose weight. Eleven patients attended 90-minute sessions where they created personalized health plans with a medical team. The goal was to see if this group approach was more effective than standar…
Phase: NA • Sponsor: Methodist Health System • Aim: Disease control
Last updated Mar 30, 2026 14:34 UTC
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Heart Drug's effectiveness in black patients under the microscope
Disease control CompletedThis study aimed to see if a heart failure medication called sacubitril/valsartan works as well for African American patients as it does for others. Researchers followed over 6,500 African American patients with weakened heart pumping to compare outcomes between this drug and sta…
Sponsor: Methodist Health System • Aim: Disease control
Last updated Mar 30, 2026 14:33 UTC
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Hospital safety check: are blood thinner doses given correctly?
Disease control CompletedThis study looked at how well hospital staff followed safety rules when giving a common blood thinner called heparin to patients. Researchers reviewed 100 adult patients who needed heparin for serious conditions like blood clots in the legs or lungs, or certain heart problems. Th…
Sponsor: Methodist Health System • Aim: Disease control
Last updated Mar 27, 2026 12:39 UTC
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New approach to halt deadly brain bleeds in blood thinner patients
Disease control CompletedThis study tested whether a fixed dose of a drug called 4-factor PCC is safe and effective at stopping brain bleeds in people taking certain blood thinners. It involved 76 adults who had a brain bleed and were taking rivaroxaban or apixaban. Researchers compared a fixed dose to a…
Sponsor: Methodist Health System • Aim: Disease control
Last updated Mar 25, 2026 14:08 UTC
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New imaging tool aims to sharpen view of bile duct problems
Diagnosis CompletedThis study tested a specialized imaging system designed to help doctors see bile duct diseases more clearly. It involved three patients who had already undergone a specific bile duct procedure using this system. The goal was to gather more information on whether the system is saf…
Sponsor: Methodist Health System • Aim: Diagnosis
Last updated Mar 27, 2026 12:38 UTC
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Common antibiotic could block deadly infection in vulnerable liver patients
Prevention CompletedThis study looked at whether the antibiotic doxycycline can safely prevent a serious abdominal infection called spontaneous bacterial peritonitis (SBP) in people with advanced liver disease. Researchers compared doxycycline to standard preventive medications in over 800 patients …
Sponsor: Methodist Health System • Aim: Prevention
Last updated Apr 03, 2026 14:43 UTC
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Can a fitness tracker get heart patients back on their feet faster?
Symptom relief CompletedThis study tested whether giving heart surgery patients a wearable activity tracker (like a Fitbit) could help them recover faster. Researchers wanted to see if the tracker motivated 12 patients to walk more after surgery and return to their normal activity levels sooner. They tr…
Sponsor: Methodist Health System • Aim: Symptom relief
Last updated Apr 03, 2026 14:43 UTC
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Freeze away the pain: new approach for broken ribs
Symptom relief CompletedThis small study tested a freezing technique called cryoanalgesia to manage pain from broken ribs. Researchers wanted to see if this method could be a good alternative to strong pain pills or epidurals, which have risks. They tracked pain levels, hospital stay length, and patient…
Sponsor: Methodist Health System • Aim: Symptom relief
Last updated Apr 02, 2026 14:57 UTC
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Study tests if work phones can stop nurse burnout
Symptom relief CompletedThis small pilot study explored ways to help nurse managers with large teams improve their work-life balance and reduce burnout. Six managers were split into two groups: one received tips to limit after-hours phone use, and the other got a separate work smartphone. The study meas…
Sponsor: Methodist Health System • Aim: Symptom relief
Last updated Mar 27, 2026 12:37 UTC
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Researchers dig into hospital records to uncover hidden infections in COVID patients
Knowledge-focused CompletedThis study looked back at the medical records of 417 adults hospitalized with COVID-19 in early 2020. Researchers wanted to find out how many patients also had other infections at the same time or developed new ones during their stay. The goal was to understand if these extra inf…
Sponsor: Methodist Health System • Aim: Knowledge-focused
Last updated Apr 04, 2026 00:35 UTC
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Blood banks ran dry during COVID-19 — this study investigates why
Knowledge-focused CompletedThis study looked back at how the COVID-19 pandemic affected the hospital's blood supply. Researchers analyzed data from 100 adult surgical patients to understand why blood products were sometimes delayed for emergency cases. The goal is to use this information to create better p…
Sponsor: Methodist Health System • Aim: Knowledge-focused
Last updated Apr 03, 2026 14:43 UTC
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Researchers track COVID-19 breakthrough cases in vaccinated texans
Knowledge-focused CompletedThis study looked at COVID-19 infections that occurred in people who were already fully vaccinated. Researchers analyzed medical records from 100 adults in Texas to understand how often these 'breakthrough' infections happened and whether getting a booster shot made a difference.…
Sponsor: Methodist Health System • Aim: Knowledge-focused
Last updated Apr 03, 2026 14:42 UTC
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Blood thinner danger in emergency surgery revealed
Knowledge-focused CompletedThis study looked at whether patients taking newer blood thinners (DOACs) bleed more during emergency abdominal surgery compared to those taking older medications like warfarin. Researchers tracked 4 patients who needed urgent surgery within 24 hours of hospital arrival. The goal…
Sponsor: Methodist Health System • Aim: Knowledge-focused
Last updated Apr 03, 2026 14:41 UTC
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Research reveals what patients talk about with clinic chaplains
Knowledge-focused CompletedThis study looked at how patients use chaplain services in a primary care clinic setting. Researchers tracked what topics 312 adult patients discussed with the clinic's full-time chaplain during their visits. The goal was to understand how spiritual and emotional support fits int…
Sponsor: Methodist Health System • Aim: Knowledge-focused
Last updated Apr 03, 2026 14:41 UTC
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New liver sharing rules drive up transplant costs, study finds
Knowledge-focused CompletedThis study looked at how a major 2020 policy change for distributing donated livers affected the costs of getting those organs to patients. Researchers analyzed data from 186 adults who received liver transplants at one center, comparing costs before and after the new rules took …
Sponsor: Methodist Health System • Aim: Knowledge-focused
Last updated Apr 02, 2026 14:57 UTC
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Survey reveals hidden toll of violence on healthcare workers
Knowledge-focused CompletedThis study aimed to measure how often violence happens to healthcare workers and how it affects them. Researchers surveyed 3,000 hospital staff about their experiences with physical and verbal aggression at work. The goal was to gather data to help hospitals better understand and…
Sponsor: Methodist Health System • Aim: Knowledge-focused
Last updated Apr 02, 2026 14:57 UTC
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Doctors question standard drug dosing for obese patients in Life-Threatening shock
Knowledge-focused CompletedThis study looked back at medical records to compare two different ways of giving blood pressure drugs to patients with septic shock, a severe infection. Researchers wanted to see if dosing based on a patient's weight leads to better or worse results than a standard fixed dose, e…
Sponsor: Methodist Health System • Aim: Knowledge-focused
Last updated Apr 02, 2026 14:57 UTC
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Researchers dig through medical records to uncover hidden links to severe liver disease
Knowledge-focused CompletedThis study looked back at the medical records of 263 adults with a confirmed liver disease called NASH to see if certain patient characteristics, other health conditions, or medications were linked to more severe liver scarring. Researchers analyzed data from 2013 to 2020 to iden…
Sponsor: Methodist Health System • Aim: Knowledge-focused
Last updated Apr 02, 2026 14:56 UTC
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Doctors look back: can a simple scan shorten hospital stays for bowel blockages?
Knowledge-focused CompletedThis study looked back at the medical records of 504 adults treated for a bowel blockage. Researchers wanted to see if using a standard imaging test, called a water-soluble contrast study, as part of a treatment plan led to better and safer care. The goal was to find out if this …
Sponsor: Methodist Health System • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:43 UTC
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Researchers track brain injury recovery in seniors
Knowledge-focused CompletedThis study observed 69 patients aged 40+ with confirmed traumatic brain injuries to collect information about their health, treatments, and recovery. Researchers tracked existing medical care without giving any experimental treatments, aiming to identify patterns and best practic…
Sponsor: Methodist Health System • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:42 UTC
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Hospitals screen for superbugs: does it prevent infections?
Knowledge-focused CompletedThis study looked back at hospital records to see if screening patients for certain hard-to-treat bacteria upon admission could predict who might later get an active infection from those same germs. Researchers analyzed data from nearly 2,900 adult patients to understand if this …
Sponsor: Methodist Health System • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:42 UTC
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Can artificial intelligence teach nurses to fight less?
Knowledge-focused CompletedThis study tested whether an artificial intelligence (AI) training program could help charge nurses get better at handling workplace conflicts. It involved 35 charge nurses from Methodist Health System. The goal was to see if this training could improve their communication and co…
Sponsor: Methodist Health System • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:42 UTC
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Doctors dig through records to uncover why some ICU pneumonias resist treatment
Knowledge-focused CompletedThis study looked back at the medical records of 132 ICU patients who developed pneumonia while in the hospital or on a ventilator. Researchers wanted to understand what factors make these infections resistant to common antibiotics. By analyzing past patient data, the goal was to…
Sponsor: Methodist Health System • Aim: Knowledge-focused
Last updated Mar 31, 2026 12:12 UTC
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Does weight slow healing? study probes Obesity's role in trauma recovery for seniors
Knowledge-focused CompletedThis study aimed to understand if obesity makes recovery more difficult for older adults after a traumatic injury. Researchers looked back at the medical records of 100 patients aged 60 and older who were hospitalized for injuries. They compared hospital stays, complications, and…
Sponsor: Methodist Health System • Aim: Knowledge-focused
Last updated Mar 31, 2026 12:11 UTC
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Doctors examine what makes neurosurgery patients happy
Knowledge-focused CompletedThis study looked back at patient satisfaction surveys from neurosurgery clinics and hospitals over five years. Researchers analyzed 1,800 surveys to understand how patients rated their care experience, including communication with doctors and overall hospital visits. The goal wa…
Sponsor: Methodist Health System • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:34 UTC
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Tracking baby health after Mom's emergency surgery
Knowledge-focused CompletedThis study aimed to understand how emergency surgeries, like for appendicitis or gallbladder issues, affect babies when performed on pregnant women. Researchers observed pregnant patients and their newborns to collect information on outcomes, comparing different surgery types and…
Sponsor: Methodist Health System • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:34 UTC
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New tool aims to spot which older trauma patients are most at risk
Knowledge-focused CompletedThis study aimed to test a new tool called the Trauma Specific Frailty Index (TSFI) to see if it could better predict which older adults (age 65+) are likely to have serious complications or a difficult recovery after a physical injury. Researchers at multiple hospitals observed …
Sponsor: Methodist Health System • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:30 UTC
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Massive trauma registry aims to save limbs and lives
Knowledge-focused CompletedThis study collected information from 999 adult patients with severe arm or leg injuries to understand how best to control bleeding and save limbs. Researchers looked at hospital records to see how emergency teams used tools like tourniquets and pressure bandages. The goal is to …
Sponsor: Methodist Health System • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:38 UTC