Methodist Health System
Clinical trials sponsored by Methodist Health System, explained in plain language.
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PCOS drug study pulled before it began
Disease control TerminatedThis study aimed to test semaglutide, a diabetes drug, in women with polycystic ovary syndrome (PCOS) to see if it could help with weight and treatment adherence. It was planned for 18-45 year old women with a BMI over 30 and a PCOS diagnosis. However, the study was withdrawn bef…
Phase: PHASE1 • Sponsor: Methodist Health System • Aim: Disease control
Last updated May 26, 2026 05:59 UTC
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Stomach balloon shows promise for fatty liver: new study tracks long-term results
Disease control ENROLLING_BY_INVITATIONThis study follows 200 adults with nonalcoholic fatty liver disease (NAFLD) who receive an intragastric balloon—a device placed in the stomach to help with weight loss. Researchers will measure changes in weight, body mass index, blood sugar, cholesterol, and liver health over at…
Sponsor: Methodist Health System • Aim: Disease control
Last updated May 26, 2026 05:48 UTC
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New program aims to stop repeat falls in seniors
Prevention ENROLLING_BY_INVITATIONThis study looks at whether a special fall prevention program can reduce the number of older adults (age 60+) who come back to the emergency room after a fall. The program includes education and standard care steps. Researchers will compare patients who took part in the program t…
Sponsor: Methodist Health System • Aim: Prevention
Last updated May 26, 2026 05:48 UTC
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COVID heart secrets revealed in record review
Knowledge-focused TerminatedThis study looks at the medical records of adults hospitalized with COVID-19 to see how the virus affects the heart. Researchers will check for conditions like heart failure, inflammation, and abnormal heart rhythms. No treatments or tests are given—just a review of existing data…
Sponsor: Methodist Health System • Aim: Knowledge-focused
Last updated May 26, 2026 05:58 UTC
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Nurse safety study pulled before it even started
Knowledge-focused TerminatedThis study aimed to understand how often nurses experience workplace violence from patients and visitors, and how prepared they feel to handle it. It planned to survey nurses at one hospital about their experiences and training. However, the study was withdrawn before enrolling a…
Sponsor: Methodist Health System • Aim: Knowledge-focused
Last updated May 26, 2026 05:55 UTC
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Cirrhosis linked to higher death risk in trauma patients
Knowledge-focused OngoingThis study looks at how liver cirrhosis impacts trauma patients' outcomes, especially death and infections. Researchers will analyze data from over 4.7 million adults in the US treated for injuries between 2010 and 2018. The goal is to understand if cirrhosis makes recovery harde…
Sponsor: Methodist Health System • Aim: Knowledge-focused
Last updated May 26, 2026 05:55 UTC
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Constipation study after back surgery withdrawn before starting
Knowledge-focused TerminatedThis study was designed to see if the drug RELISTOR could help relieve constipation caused by painkillers after lower back surgery. It planned to compare patients who received RELISTOR with those who got standard care. However, the study was withdrawn before any participants were…
Sponsor: Methodist Health System • Aim: Knowledge-focused
Last updated May 26, 2026 05:55 UTC
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Heart test race gap under investigation
Knowledge-focused ENROLLING_BY_INVITATIONThis study looks at whether standard blood tests for heart failure show different results in African American patients compared to Caucasian patients. Researchers will review medical records of 400 adults newly diagnosed with heart failure. The goal is to see if current tests mis…
Sponsor: Methodist Health System • Aim: Knowledge-focused
Last updated May 26, 2026 04:38 UTC
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ER drug mystery: which combo works best for trauma breathing tubes?
Knowledge-focused TerminatedThis study planned to look back at medical records of trauma patients who needed a breathing tube in the emergency room. The goal was to find out which drug combinations are most commonly used and how they affect patient outcomes. However, the study was withdrawn before enrolling…
Sponsor: Methodist Health System • Aim: Knowledge-focused
Last updated May 26, 2026 04:37 UTC
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Study on extra antibiotics for leg fractures pulled before it began
Knowledge-focused TerminatedThis study aimed to find out if adding a strong antibiotic (aminoglycoside) to the usual antibiotic helps patients with open leg fractures. It planned to include adults with moderate to severe open fractures. However, the study was withdrawn before enrolling any participants, so …
Phase: PHASE3 • Sponsor: Methodist Health System • Aim: Knowledge-focused
Last updated May 26, 2026 04:37 UTC
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New protocol aims to improve care for pancreatitis patients
Knowledge-focused OngoingThis study is looking at how well a standard treatment plan works for people with acute pancreatitis, a sudden inflammation of the pancreas. Researchers are tracking 500 adults to see if following this plan leads to shorter hospital stays and better recovery. The goal is to find …
Sponsor: Methodist Health System • Aim: Knowledge-focused
Last updated May 22, 2026 14:04 UTC
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Are repeat back surgeries riskier? new study investigates
Knowledge-focused OngoingThis study looks at medical records from 3,500 adults who had a type of back surgery called ALIF between 2010 and 2020. Researchers want to see if death rates have dropped over time and whether having a second surgery is riskier than the first. The goal is to find ways to make re…
Sponsor: Methodist Health System • Aim: Knowledge-focused
Last updated May 22, 2026 14:03 UTC
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Local hospital investigates hidden virus threat in Dual-Organ transplants
Knowledge-focused ENROLLING_BY_INVITATIONThis study reviews medical records of 50 adults who received a simultaneous liver-kidney transplant at Methodist Dallas Medical Center between 2015 and 2020. The goal is to find out how many of them developed BK virus in their blood, a virus that can harm the new kidney. No new t…
Sponsor: Methodist Health System • Aim: Knowledge-focused
Last updated May 22, 2026 14:02 UTC
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Nurse rudeness study pulled before starting
Knowledge-focused TerminatedThis study aimed to understand how rude behavior between nurses affects their sense of meaning, joy, and confidence at work. Researchers planned to survey nurses who provide direct patient care at several hospitals. However, the study was withdrawn before any participants were en…
Sponsor: Methodist Health System • Aim: Knowledge-focused
Last updated May 22, 2026 13:54 UTC
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New registry aims to improve care for rare aortic injuries
Knowledge-focused OngoingThis study is gathering information from 300 adults who have a blunt injury to the main artery in the chest (the thoracic aorta). Researchers will look at how the injury is found, treated, and how patients recover over time. No new treatments or tests are given—the goal is to lea…
Sponsor: Methodist Health System • Aim: Knowledge-focused
Last updated May 22, 2026 13:53 UTC
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Liver tumor treatment study halted before start
Knowledge-focused TerminatedThis study aimed to review past patient records to understand how well radioembolization works for liver tumors, including intrahepatic cholangiocarcinoma and metastatic liver cancer. The goal was to learn about survival and tumor recurrence. However, the study was withdrawn befo…
Sponsor: Methodist Health System • Aim: Knowledge-focused
Last updated May 20, 2026 11:56 UTC
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Study on hormone differences in men with liver disease and low blood pressure withdrawn
Knowledge-focused TerminatedThis study was designed to measure and compare estrogen and testosterone levels in men with cirrhosis who also have low blood pressure versus those with normal blood pressure. The goal was to better understand why low blood pressure occurs in cirrhosis. However, the study was wit…
Sponsor: Methodist Health System • Aim: Knowledge-focused
Last updated May 19, 2026 12:01 UTC
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Massive GI study tracks 1000 patients over 25 years
Knowledge-focused ENROLLING_BY_INVITATIONThis study gathers information from 1,000 adults treated for benign or malignant gastrointestinal diseases between 2005 and 2030. Researchers will review medical records to see how patients fared after treatment, focusing on survival, symptoms like heartburn and swallowing troubl…
Sponsor: Methodist Health System • Aim: Knowledge-focused
Last updated May 18, 2026 12:07 UTC