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New study looks at best acyclovir dose for obese patients with brain infection

NCT ID NCT05127395

First seen Mar 23, 2026 · Last updated May 25, 2026 · Updated 8 times

Summary

This study looked back at medical records of 50 obese adults (BMI over 30) who were treated for HSV encephalitis, a serious brain infection, with the drug acyclovir. The goal was to see if using ideal body weight or adjusted body weight to calculate the dose changed the chance of dying in the hospital. The study did not test a new treatment but aimed to gather information to improve dosing guidelines.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Methodist Charlton Medical Center

    Dallas, Texas, 75237, United States

Conditions

Explore the condition pages connected to this study.