Mansoura University
Clinical trials sponsored by Mansoura University, explained in plain language.
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New digital brace aims to fix Kids' underbite without surgery
Disease control ENROLLING_BY_INVITATIONThis study tests a custom-made digital dental device (Digital Bonded Reverse Twin Block) in 21 children aged 8-11 with mild underbite (Class III malocclusion). The device is bonded to the teeth and uses angled planes to gently shift the jaw and teeth into a better position. Resea…
Phase: PHASE1 • Sponsor: Mansoura University • Aim: Disease control
Last updated Apr 30, 2026 15:49 UTC
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New hope for kidney patients: diabetes drugs tested for nephrotic syndrome
Disease control OngoingThis study tests whether two diabetes drugs (dapagliflozin and empagliflozin) can help adults with nephrotic syndrome, a kidney condition causing protein leakage and swelling. 75 participants will receive either one of the drugs plus standard care, or standard care alone, and be …
Phase: PHASE2, PHASE3 • Sponsor: Mansoura University • Aim: Disease control
Last updated Apr 30, 2026 15:48 UTC
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Fish oil may regrow tooth roots in kids, study finds
Disease control OngoingThis study tests whether placing omega-3 fatty acids inside a damaged, immature tooth can help it regrow root length and dentin wall thickness. Twenty patients aged 6 to 28 with a dead tooth nerve will receive either the omega-3 treatment or the standard blood-clot method. The go…
Phase: NA • Sponsor: Mansoura University • Aim: Disease control
Last updated Apr 29, 2026 15:14 UTC
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New dental material may stop white spots during invisible braces
Prevention OngoingThis study tests whether using a fluoride-releasing composite resin for aligner attachments can prevent white spot lesions (early cavities) compared to standard attachments. Twenty-four people aged 16-24 with mild crowding will have one side of their mouth get the fluoride materi…
Phase: NA • Sponsor: Mansoura University • Aim: Prevention
Last updated May 01, 2026 16:00 UTC
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Fluoride shield for clear aligners: study tests white spot prevention
Prevention OngoingThis study tests whether applying fluoride varnish to teeth can prevent white spot lesions (early cavities) in people using clear aligners. Twenty-five participants aged 16-24 with mild crowding will have one side of their mouth treated with fluoride varnish and the other side le…
Phase: NA • Sponsor: Mansoura University • Aim: Prevention
Last updated Apr 26, 2026 20:01 UTC
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Less drilling, less pain? new dental surgery approach shows promise
Symptom relief OngoingThis study compares two ways to perform dental root-end surgery. The standard method removes the entire infected area and uses stitches. The new method removes only part of the lesion and uses a medical glue to close the wound. The goal is to see if the gentler approach leads to …
Phase: NA • Sponsor: Mansoura University • Aim: Symptom relief
Last updated May 01, 2026 16:00 UTC
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Aligners vs. braces: which is better for crowded teeth?
Symptom relief OngoingThis study compares clear aligners and traditional braces for treating mild to moderate dental crowding in adults. Researchers will measure changes in jawbone thickness and height, as well as tooth movement. The goal is to see which method works better and causes fewer side effec…
Phase: NA • Sponsor: Mansoura University • Aim: Symptom relief
Last updated Apr 30, 2026 15:51 UTC
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Mirror trick may heal Stroke-Damaged arms
Symptom relief OngoingThis study tests whether mirror therapy can help people who have had a stroke regain movement and reduce pain in a weakened arm. 72 participants with a first-time stroke will be randomly assigned to receive mirror therapy or standard care. The goal is to see if this simple, non-i…
Phase: NA • Sponsor: Mansoura University • Aim: Symptom relief
Last updated Apr 29, 2026 15:04 UTC
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New painkiller combo could extend relief after knee surgery
Symptom relief ENROLLING_BY_INVITATIONThis study tests whether adding dexmedetomidine to standard spinal anesthesia can provide longer pain relief after knee surgery. About 100 adults aged 18-60 having elective knee surgery will participate. The main goal is to measure how long it takes before patients need additiona…
Phase: NA • Sponsor: Mansoura University • Aim: Symptom relief
Last updated Apr 29, 2026 15:03 UTC
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New study tests fun videos and acupressure to calm kids at the dentist
Symptom relief ENROLLING_BY_INVITATIONThis study looks at whether watching a video or getting a gentle acupoint massage can help children feel less anxious and experience less pain when having a baby tooth pulled. About 69 healthy kids aged 5 to 8 will take part. Their anxiety will be measured by heart rate and a pic…
Phase: NA • Sponsor: Mansoura University • Aim: Symptom relief
Last updated Apr 26, 2026 20:02 UTC
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Scientists check how teeth aligners hold up after two weeks of wear
Knowledge-focused OngoingThis study looks at how clear aligners (like Invisalign) change after being heated and shaped, and after two weeks of wear in the mouth. Researchers will compare single-layer and multi-layer aligners by measuring surface roughness, hardness, and thickness. Twenty people with mild…
Phase: NA • Sponsor: Mansoura University • Aim: Knowledge-focused
Last updated May 01, 2026 16:00 UTC
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Gum graft showdown: which technique wins for dental implants?
Knowledge-focused OngoingThis study looks at two different ways to place gum grafts during dental implant surgery to see which method helps the gum heal better and reduces bone loss around the implant. It involves 20 healthy adults who need a single tooth replaced. The goal is to find the best technique …
Phase: NA • Sponsor: Mansoura University • Aim: Knowledge-focused
Last updated May 01, 2026 15:57 UTC
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Denture attachment method may affect bone loss around implants
Knowledge-focused OngoingThis study compares two methods of picking up attachments for lower dentures supported by two implants: one using a digital scan before recording jaw relations, and the other using a traditional intraoral pickup. Ten adults with healthy gums and enough jawbone will be followed fo…
Phase: NA • Sponsor: Mansoura University • Aim: Knowledge-focused
Last updated Apr 30, 2026 15:51 UTC
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Braces vs. aligners: which moves teeth better? new study reveals biological clues
Knowledge-focused OngoingThis study looks at how clear aligners and traditional braces move teeth in 20 adults with mild crowding. Researchers will measure certain chemicals in the gums and track tooth movement using 3D scans to see if one method works differently than the other. The goal is to help dent…
Phase: NA • Sponsor: Mansoura University • Aim: Knowledge-focused
Last updated Apr 29, 2026 15:05 UTC
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Dental implant showdown: full guidance vs. partial guidance
Knowledge-focused OngoingThis study compares two ways of placing all-on-4 dental implants (full guidance vs. partial guidance) in 16 people with no teeth. Researchers use 3D scans and X-rays to measure how accurate the implant positions are and how well the final teeth fit. Participants are followed for …
Phase: NA • Sponsor: Mansoura University • Aim: Knowledge-focused
Last updated Apr 29, 2026 15:03 UTC