Fish oil could help Kids' teeth regrow roots, small trial hints
NCT ID NCT07371416
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether placing omega-3 fatty acids inside a damaged tooth can help it regrow root length and dentin, compared to the standard method of inducing bleeding. Twenty patients aged 6 to 28 with immature permanent teeth that have died due to injury or decay will be treated. The goal is to see if this natural substance can improve tooth healing and strength.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Omega-3 fatty acids
- What this could lead to
- If it works, this could offer a simpler, natural way to help damaged teeth in children and young adults regrow root structure and avoid extraction.
- What could go wrong
- This is a very small early-stage trial with only 20 participants, so results may not apply widely. The treatment is experimental and may not improve outcomes over standard care.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
About 20 people
The number the study aims to enrol. It can still change while the study runs.
- Started
-
Oct 2025
- Expected to finish
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Jan 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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6 to 28 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients aged between 6 and 28 years. * Systemically healthy patients with no history of systemic diseases. * Patients with necrotic immature permanent teeth due to trauma and/or caries. * Preoperative radiographic evidence of incomplete root formation. * Wide apical foramen (apical diameter ≥ 1 mm). * Thin dentinal walls on preoperative radiographs. Exclusion Criteria: * Patients with known allergy to any of the drugs used in the study. * Patients with systemic diseases or medically compromised conditions. * Grossly decayed or fractured teeth requiring post and core restorations. * Presence of draining sinus tract. * Presence of periodontal pockets. * Radiographic evidence of external or internal root resorption. * Patients with a history of major surgeries (e.g., cardiac surgery, kidney transplantation). * Patients undergoing hemodialysis.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Mansoura University
Al Mansurah, 111, Egypt
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Other studies related to the condition(s) this trial covers.
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