Mansoura University

This study compares custom-made and ready-made Carriere motion appliances for correcting Class II malocclusion (overbite) in 24 teenagers aged 12-15. The goal is to see which device achieves a proper bite faster and with better patient satisfaction. Participants will be randomly …

This study tests two types of 3D-printed braces to correct underbites in teens aged 11-14. Sixty participants will be split into three groups: one getting a MARA appliance, one getting a fixed twin block, and one getting no treatment. Researchers will measure changes in jaw and t…

This study tests a custom 3D-printed device to widen the upper jaw in 16 young adults aged 18-30. The expander is attached directly to the bone with mini-screws, avoiding pressure on teeth. Researchers will use 3D scans to measure how the jaw bones and teeth move over three month…

This study tests three methods to restore the small triangle of gum tissue between teeth that can be lost due to gum disease. The approaches are: injecting hyaluronic acid (a filler), injecting a special blood-derived material (ALB-PRF) that lasts longer, or a small surgical proc…

This study looks at two types of tooth-colored filling materials (ormocer and methacrylate-based bulk-fill) and different polishing methods for cavities near the gum line (class V). About 25 adults with these cavities will receive fillings and be followed for 2 years to see which…

This study tests whether two diabetes drugs (dapagliflozin and empagliflozin) can help adults with nephrotic syndrome, a kidney condition that causes protein leakage and swelling. About 75 participants will receive either one of these drugs plus standard care, or standard care al…

This study looks at three types of tooth-colored onlays (custom-made fillings) for back teeth with deep cavities that go below the gum line. Researchers will first build up the cavity edge, then place three different onlays in each of 18 adult patients. They will check the fillin…

This study tests whether a stellate ganglion block (a nerve injection in the neck) given before mastectomy can prevent depression and chronic pain afterward. Researchers will compare 140 women who receive the block to those who do not, tracking depression scores and pain levels f…

This study tests whether injecting the painkiller ketorolac into a leg during surgery can reduce pain after the operation. 76 adults having lower leg surgery with a tourniquet will receive either ketorolac or a saltwater solution. The main goal is to see how long pain relief last…

This study tests three different ways of taking dental impressions to make 3D-printed implant overdentures for people with no teeth. Sixteen participants will try each method for three months, and researchers will measure how well they chew and how satisfied they are. The goal is…

This study tests whether a nebulized steroid (budesonide) can prevent stridor—a noisy, difficult breathing caused by airway swelling—after jaw surgery. 62 adults having elective jaw surgery will receive either budesonide or a placebo before surgery. The goal is to see if the ster…

This study tests two once-daily pills—tadalafil and solifenacin—in 480 women with overactive bladder (OAB) to see which one better reduces sudden urges and frequent bathroom trips. Participants will take the medicine for 12 weeks and track their symptoms in a bladder diary. The g…

This study compares a new shockwave treatment to a standard daily pill for women with overactive bladder. Seventy women will receive either weekly shockwave sessions for 8 weeks or a daily medication for 12 months. Researchers will track symptom changes and quality of life over a…

This study tests whether taking a daily low-dose ED pill plus a stronger on-demand pill can help men whose erectile dysfunction doesn't improve with standard medication alone. About 500 men will be randomly assigned to receive either the combination or a placebo plus the on-deman…

This study tests whether injecting botulinum toxin (like Botox) into the surgical wound can reduce scarring after cleft lip repair. About 32 people with mild to severe unilateral cleft lip will receive the injection, and scar width and appearance will be measured. The goal is to …

This study looks at whether numbing the upper and lower jaw nerves before surgery can lower pain and the need for extra pain medicine after jaw surgery. About 60 adults having planned jaw surgery will take part. The goal is to see if this nerve block helps control pain better tha…

This study tests if special pelvic floor exercises can reduce or stop the small urine leak some men experience after urinating. Researchers will compare targeted exercises to general exercises in 120 men aged 18 to 40 over 12 weeks. The goal is to see if these exercises improve s…

This study tests whether a combination of two drugs (mirabegron and solifenacin) works better than the standard drug (desmopressin) for children who wet the bed. About 120 children will take one of the treatments daily for 3 months. The goal is to see which approach reduces the n…

This study looks at 200 healthy women having a planned C-section under spinal anesthesia. It compares two drugs, norepinephrine and ephedrine, to see which one better keeps the heart pumping blood effectively. Researchers use ultrasound to measure heart function at key times duri…