Mansoura University

This study compares two drugs, milrinone and epinephrine, to treat right heart dysfunction that can occur after cardiac surgery. The trial will enroll 102 adults undergoing heart surgery with a heart-lung machine. The goal is to see which drug better improves right heart function…

This study tests a modified surgical technique called periosteal inhibition to see if it helps preserve bone around dental implants placed right after tooth extraction. Thirty adults with a non-restorable back tooth and thin buccal bone will be randomly assigned to get either the…

This study compares two different power levels of a holmium laser used during a minimally invasive surgery for large kidney stones (over 20 mm). Seventy adults will be randomly assigned to receive either high-power (up to 40 W) or low-power (10-20 W) laser treatment. The main goa…

This study tests whether nightly low-dose atropine eye drops can slow the progression of nearsightedness (myopia) in children. Forty-five kids aged with worsening myopia will receive atropine in one eye and a placebo in the other for 24 months. Researchers will measure changes in…

This study will compare two advanced, suction-assisted surgeries for removing kidney stones that are 2-3 cm in size. About 280 adults across nine hospitals in Egypt will be randomly assigned to either FANS-based flexible ureteroscopy or suction mini-PCNL. The main goal is to see …

This study tests whether adding finerenone to standard heart failure treatment (an SGLT2 inhibitor) can reduce deaths and hospitalizations. About 60 adults aged 18-65 with newly diagnosed heart failure will be split into two groups: one gets the standard drug alone, the other get…

This study compares two ways to prevent heavy bleeding after a planned C-section: one drug (carbetocin) alone versus the same drug plus a slow drip of another (oxytocin). About 332 women having planned C-sections will take part. The goal is to see if the single drug works just as…

This study compares two dental appliances—a palatal crib and bonded spurs—to treat anterior open bite in children aged 7 to 12. Twenty kids will be randomly assigned to one of the two braces and followed for 6 months. The goal is to see which appliance works better and is more co…

This study tests whether low-dose colchicine, a drug used for gout, can reduce inflammation and symptoms in people with autoimmune or subacute thyroiditis. About 300 adults will be randomly assigned to colchicine, corticosteroids, or supportive care. The goal is to see if colchic…

This study compares two diabetes pills, imeglimin and metformin, in adults recently diagnosed with type 2 diabetes who have not taken any diabetes medication before. The goal is to see which drug better improves how cells' energy factories (mitochondria) work, measured by a blood…

This study looks at whether squeezing a handgrip device or walking is better at lowering blood pressure in people with high blood pressure. About 99 adults with stage 1 hypertension will be assigned to one of the two exercises. The goal is to see which activity leads to a greater…

This study will test whether teaching mothers a laid-back breastfeeding position improves their experience and comfort compared to the usual cradle hold. 168 women who have given birth before and are planning a C-section will be trained during pregnancy and followed after birth. …

This study compares taking tamsulosin every day versus every other day in 288 men aged 40 and older with enlarged prostate and moderate-to-severe urinary symptoms. The goal is to see if the every-other-day schedule controls symptoms just as well while possibly causing fewer sexua…

This study will test whether applying ice packs to the perineum (the area between the vagina and anus) can reduce pain in women who had an episiotomy during a normal vaginal birth. One hundred healthy women who just gave birth will be enrolled. Half will receive cryotherapy (ice …

This study tests whether a structured marital adjustment program can help emotionally divorced wives feel more connected to their husbands. The program includes educational sessions on communication, coping, and problem-solving. Researchers will measure emotional divorce levels b…

This study tests whether adding gabapentin to the standard drug solifenacin works better than solifenacin alone for women with overactive bladder. Sixty women will be randomly assigned to one of the two treatments and followed for 3 months. The goal is to see if the combination i…

This study tests two medicines, phenobarbital and levetiracetam, to see which works better and is safer for stopping seizures in newborns with moderate to severe brain injury from lack of oxygen (HIE). About 66 babies will receive one of the drugs, and doctors will check if seizu…

This study tests whether a natural compound called phenolic complex k110-42 can improve attention and thinking in children with Down syndrome. About 108 children aged 4 to 8 will take the compound and have their cognitive skills measured with standard tests. The goal is to ease s…

This study tests whether Oketani massage, a gentle breast massage technique, helps first-time mothers breastfeed more successfully. Researchers will measure how well babies latch, how comfortable moms feel, and overall breastfeeding confidence. The study involves 100 women who ha…

This study tests whether placing an ice bag on the upper thigh (groin area) after a common heart procedure called PCI can lower pain and reduce bruising. About 60 adults with coronary artery disease who had the procedure through the femoral artery will take part. Researchers will…

This study tests whether adding neostigmine to a standard numbing medicine (bupivacaine) in a belly-wall nerve block can improve pain control after cesarean delivery. About 58 women having planned C-sections will receive either the combo or the standard block alone. The goal is t…

This study will test whether structured educational sessions can improve how maternity nurses care for patients experiencing abortion. Sixty nurses will attend training sessions covering abortion care practices, including lectures and demonstrations. Researchers will observe thei…

This study will enroll 36 children aged 8 to 13 with crossbite who need a palatal expander. Researchers will compare three ways to make the device: fully traditional (molding by hand), hybrid (hand molding plus computer design), and fully digital (3D scanning plus computer design…

This study tests whether smart mind maps—visual tools that combine drawings and keywords—can help nurses in the pediatric intensive care unit (PICU) safely administer high-alert medications (drugs that can cause serious harm if given incorrectly). The researchers will train 70 nu…

This study tests whether a short empathy training program helps maternity nurses communicate more compassionately with women in labor. About 45 nurses will attend three training sessions, and both nurses and the women they care for will fill out questionnaires to measure changes …

This study tests a special program designed to improve critical thinking, reflective thinking, and motivation to learn in nursing students. About 243 students will take part in the program, which focuses on building skills like problem-solving and open-mindedness. Researchers wil…

This study will test whether a new step-by-step emergency care plan helps maternity nurses provide better care during urgent situations. Researchers will observe 60 nurses working in delivery rooms and emergency operating rooms. The goal is to see if the protocol improves how nur…