Heart failure drug combo aims to cut hospital stays
NCT ID NCT07351864
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether adding finerenone to standard heart failure treatment (an SGLT2 inhibitor) can reduce deaths and hospitalizations. About 60 adults aged 18-65 with newly diagnosed heart failure will be split into two groups: one gets the standard drug alone, the other gets both drugs. Researchers will track heart-related deaths, hospital stays, and side effects like potassium levels.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 4
Runs after approval, following long-term safety and how well the treatment works in everyday use.
- Participants
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About 60 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Jan 2026
An estimate. Start dates often move.
- Expected to finish
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Jul 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Male and female patients aged 18 - 65 years. * Newly diagnosed with HFrEF or HFpEF. * Clinically stable and eligible to start SGLT2 inhibitors ± Finerenone therapy. Exclusion Criteria: * Patients with stroke. * eGFR \<25 mL/min. * HF secondary to congenital heart disease or pulmonary hypertension * Use intravenous inotropes. * Patients needing cardiac transplantation. * Known allergy to study medications.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Mansoura University Hospitals, Cardiology Department (Specialized Medical Hospital)
Al Mansurah, Egypt
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can daily mindful breathing ease heart failure symptoms?
- Can a smartphone app keep heart failure patients out of the hospital?
- Can better training get doctors to talk about what matters most to dying veterans?
- Can AI read heart ultrasounds as well as trained sonographers?
- Can modern heart failure drugs reverse damage in three months?