New gum surgery technique aims to cut pain and swelling
NCT ID NCT07353580
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a less invasive surgical approach for treating persistent tooth infections. Instead of removing all infected tissue and using stitches, surgeons remove only part of the tissue and seal the area with a medical glue. The goal is to see if this method reduces pain, swelling, and other complications after surgery. Twenty-four adults with failed root canals are being followed for one year.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Selective curettage and cyanoacrylate tissue adhesive
- What this could lead to
- If successful, this could lead to a less painful and faster-recovering surgical option for persistent tooth infections.
- What could go wrong
- This is a small, early-stage trial with only 24 participants, so results may not apply to everyone. The procedure is still experimental and may not improve healing over standard methods.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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24 people
The number who actually took part.
- Started
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Dec 2024
- Expected to finish
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Feb 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Age 18 years and older consenting to the surgical procedure as well as agreeing to preoperative and at least 1 follow-up CBCT evaluation. 2. Noncontributory medical history (American Society of Anesthesiologists class I, II). 3. Teeth with periapical lesions that had been previously treated or retreated but symptoms persist or recurrent. 4. Radiographic presence of true endodontic lesion close to vital critical structure. Exclusion Criteria: 1. Nonconsenting patients and patients younger than 18 years of age. 2. Medical history with the American Society of Anesthesiologists class III to V. 3. Insufficient coronal restoration. 4. Nonrestorability or traumatized teeth. 5. Mobility \> 1. 6. Vertical root fracture.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Faculty of Dentisrty , Mansoura University
Al Mansurah, Egypt