New combo treatment aims to quiet jaw pain without surgery
NCT ID NCT07401745
First seen Feb 12, 2026 · Last updated May 20, 2026 · Updated 12 times
Summary
This study tests whether wearing a custom mouth splint and getting a granisetron injection into the jaw muscle can reduce pain from temporomandibular disorders (TMD). About 48 adults with jaw muscle pain will be split into three groups: splint alone, splint plus granisetron, or splint plus lidocaine. Researchers will measure pain, jaw movement, and clicking over 6 months to see which approach works best.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Faculty of Dentistry, Mansoura University
Al Mansurah, Dakahlia Governorate, 35511, Egypt
Conditions
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