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Custom tooth-shaped implants take on standard screws in denture support trial

NCT ID NCT07284680

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares a custom-made bio-implant (shaped like a natural tooth root) to a standard screw-type implant for supporting partial dentures in people missing back teeth. Eight participants with a specific tooth arrangement received both types of implants. Researchers will measure bone levels and gum health around the implants and nearby teeth at 0, 3, and 6 months after the final denture is placed.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
bio-implant root analogue (custom-shaped implant) and conventional screw-type implant
What this could lead to
If successful, this could show that a custom-shaped bio-implant works as well as or better than standard screw implants for supporting partial dentures, potentially offering a more natural option.
What could go wrong
This is a very small study with only 8 participants, so results may not apply to everyone. It is also early-stage and only follows patients for 6 months, so long-term success is unknown.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

8 people

The number who actually took part.

Started

Dec 2022

Expected to finish

Dec 2025

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

45 to 65 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * The patients had bilateral mandibular free-end partially edentulous cases with a pier abutment or a planned presence of pier abutment. * The edentulous space mesial to the pier abutment has a hopeless tooth or root that was used for bio-implant insertion or conventional screw-type implants. * Healthy patients with no systemic disease that can affect the implant surgery. This was verified by medical history in addition to a report from the physician. * The patients have had dentulous maxillary jaw and mandibular free-end saddle for at least 6 months. * Class I maxillo-mandibular relationship with adequate inter-arch distance. Exclusion Criteria: * Patients with metabolic disorders that affect osseointegration such as uncontrolled diabetes mellitus, immune disorders, and osteoporosis. * Patients with heavy smoking habit * Patients complaining of severe temporomandibular joint disorder.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Mansoura University

    Al Mansurah, Dakahlia Governorate, 7650001, Egypt

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