Jonsson Comprehensive Cancer Center

This early-phase study is testing the safety and best dose of a new type of CAR-T cell therapy for patients with B-cell lymphomas or chronic lymphocytic leukemia that have come back or not responded to standard treatments. Doctors modify a patient's own immune T-cells to recogniz…

This study is testing a two-part treatment for prostate cancer that has come back and spread to a few other places in the body. Participants receive hormone-blocking drugs for six months, along with a short, highly focused course of radiation aimed directly at the tumors. The goa…

This study is testing whether taking two oral drugs together works better than either alone for people with a fast-growing type of lung cancer that has returned after initial chemotherapy. The drugs, talazoparib and temozolomide, aim to stop cancer cells from growing by damaging …

This trial is testing a combination of three drugs (niraparib, temozolomide, and atezolizumab) to see if they work better together to control advanced cancers. The study first finds the safest dose, then compares the three-drug combo to a single drug for patients with extensive-s…

This study is testing a shorter, more targeted form of radiation therapy for men whose prostate cancer was surgically removed but who are at high risk of it coming back. The goal is to see if this precise, 5-session treatment can effectively control the cancer while causing fewer…

This study is testing a two-part treatment for advanced cancer. Doctors take a patient's own white blood cells, genetically modify them to recognize a specific cancer protein (NY-ESO-1), and infuse them back. This is combined with a vaccine made from the same protein to boost the…

This study is testing a combination of three drugs for people with advanced lung cancer that has a specific genetic change (EGFR mutation) and has stopped responding to the usual treatment. The goal is to see if adding two antibody drugs (trastuzumab and necitumumab) to the stand…

This early-stage trial is testing whether adding the immunotherapy drug pembrolizumab to standard chemotherapy works better for treating advanced small cell or neuroendocrine cancers of the bladder, urethra, or prostate. The study will enroll about 15 participants with cancer tha…

This study is testing a focused, high-dose radiation treatment called SBRT for men with high-risk prostate cancer that hasn't spread. The goal is to see if this shorter treatment schedule (5 sessions over 2 weeks) can effectively control the cancer while minimizing side effects a…

This early-stage study is testing the safety of combining two immunotherapy drugs, nivolumab and BO-112, given before surgery for patients with operable soft tissue sarcoma. The goal is to see if stimulating the immune system to attack the tumor before it is removed can improve o…

This study is testing whether a plant-based nutrition drink can help people with head and neck cancer avoid needing a feeding tube during their chemoradiation treatment. Researchers want to see if this easy-to-digest, allergen-free drink provides enough calories and protein to ma…

This is a small, early-stage study to see if a personalized vaccine is safe for patients with a rare and aggressive brain tumor called H3 G34-mutant glioma. The vaccine is made from the patient's own immune cells and is designed to teach the body to attack the tumor. Researchers …

This study is testing a new way to deliver radiation therapy along with standard chemotherapy for people with stage II or III non-small cell lung cancer that cannot be removed by surgery. The goal is to see if a more targeted, higher-dose radiation schedule can kill more cancer c…

This study is comparing two different imaging methods used to guide radiation treatment for prostate cancer. It aims to see if using MRI scans to guide the radiation causes fewer side effects, like urinary or bowel problems, compared to the standard CT scan method. About 180 men …

This study is testing whether combining a targeted form of internal radiation (brachytherapy) with immunotherapy drugs can help control advanced gynecologic cancers that have stopped responding to standard platinum-based chemotherapy. It aims to see if this two-pronged approach i…

This study is testing a new type of MRI scan designed to see brain tumors in more detail. It aims to help doctors better detect, understand, and potentially track how tumors respond to treatment. The study involves patients with glioma brain tumors who are scheduled for surgery o…

This study is testing a new way to find prostate cancer in men whose previous biopsy results were unclear or negative. Researchers use a special radioactive tracer that sticks to prostate cancer cells, which shows up on a PET/CT scan. This scan then guides where to take biopsy sa…

This study compares two molecular tests used to evaluate thyroid nodules that have unclear biopsy results. The goal is to determine which test is better at identifying which nodules are truly cancerous and which are benign, helping patients avoid surgery they don't need. Research…

This study is testing whether a specialized imaging scan called MIBI SPECT/CT can help doctors better identify the type of kidney tumor a patient has. The goal is to see if this scan provides clearer information that helps patients and doctors choose the most appropriate treatmen…

This study is testing a practical program to get more people screened for colorectal cancer, which is a leading cause of cancer deaths. It focuses on helping low-income and ethnic minority patients, who often face barriers to screening. The program provides clinics with training,…

This study is testing whether the gentle mind-body exercise Tai Chi can help improve chronic insomnia in women who have survived breast cancer. Researchers are comparing Tai Chi to standard cognitive behavioral therapy (CBT) to see which is better at improving sleep quality, redu…

This study is testing if using Soylent, a liquid meal replacement, can help patients with head and neck cancer avoid needing a feeding tube during their intensive chemoradiation treatment. The goal is to see if better nutrition from Soylent can reduce malnutrition and the need fo…

This study is testing whether watching educational videos can help people who have survived a rare eye cancer called uveal melanoma. The goal is to see if changing how patients think about their illness can reduce feelings of anxiety and depression during survivorship. About 108 …

This early-phase study is testing a new imaging agent called 68Ga-FAPI-46 to see where it goes in the body of patients with various cancers. Researchers will give participants the tracer and then perform PET/CT scans to see how it collects in both normal and cancerous tissues. Th…

This study is testing whether a genetic test can predict which prostate cancer patients are at high or low risk for serious urinary and bowel side effects from a specific type of radiation therapy. About 208 men with early-stage prostate cancer will take the test, and then discus…