Institut Claudius Regaud

This study is for people with a type of head and neck cancer that has come back or spread. It tests whether using only 4 cycles of chemotherapy (instead of the usual 6) together with the immunotherapy drug pembrolizumab can still control the cancer while causing fewer side effect…

This study is for people with metastatic bladder cancer that has not gotten worse after initial chemotherapy and has three or fewer remaining tumors. It tests whether adding focused radiation to standard care can help them live longer. About 130 participants will be randomly assi…

This study looks at whether adding 4 cycles of chemotherapy around the time of surgery can help prevent the spread of soft tissue sarcoma in people at high risk. About 600 adults with resectable tumors will be screened, and 250 high-risk patients will be randomly assigned to stan…

This study tests if a personalized program of exercise, physical therapy, and nutrition before surgery can improve recovery and independence for people with bone or soft-tissue sarcoma in the arm or leg. About 53 participants will be followed for 2 years after surgery. The goal i…

This study is looking at whether a blood test (liquid biopsy) can detect prostate cancer cells as well as a special PET scan does. Researchers will take blood samples from 80 men with prostate cancer before their PET scan and compare the results. The goal is to see if the blood t…

This study will collect tumor and blood samples from 1100 people with various cancers (like head and neck, ovarian, and lung cancer) to measure how active certain immune cells are. The goal is to learn more about the body's natural immune response to cancer, not to test a new tre…

This study explores whether using alternative or complementary therapies, like turmeric supplements, influences how consistently breast cancer patients take their prescribed tamoxifen. Researchers will follow 200 women with early-stage hormone-dependent breast cancer for one day …

This study tracks 770 adults with advanced solid cancers (like lung, head and neck, melanoma, or bladder cancer) who are receiving immunotherapy. Researchers collect tumor and blood samples to find biological markers that predict how well the treatment works or causes side effect…

This study aims to understand why some ovarian cancers become resistant to platinum-based chemotherapy. Researchers will follow 600 patients for 5 years, collecting medical data and biological samples (blood, tumor tissue, and fluid from the abdomen) during standard care. No extr…

This study follows 130 children who had radiation for a brain tumor between ages 4 and 12. Researchers will test their memory and thinking skills 2 and 4 years after treatment, and also look at brain scans to see how radiation dose to the hippocampus relates to memory problems. T…

This study collects tumor samples from 1,050 people with early or metastatic breast cancer to analyze fat storage and protein patterns inside cancer cells. Researchers want to see how these features differ across breast cancer subtypes. No treatment is given—the goal is to gather…

This study is gathering medical information and biological samples from 500 people with rare soft tissue sarcomas. The goal is to learn how the immune system interacts with these rare cancers, which could help doctors develop better treatments in the future. Participants include …

This study aims to find out why certain breast cancers become resistant to PARP inhibitor drugs. Researchers will analyze tumor and blood samples from 120 patients with advanced breast cancer who have a BRCA1/2 gene mutation. The goal is to identify biological markers that predic…

This study looks at whether a simple blood test can find genetic changes in tumor DNA that signal ovarian cancer is coming back. It involves 130 women with BRCA gene mutations who are taking a maintenance drug called Olaparib (with or without bevacizumab) after initial treatment.…