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New chemo combo aims to stop sarcoma spread in High-Risk patients

NCT ID NCT04307277

First seen Feb 11, 2026 · Last updated May 25, 2026 · Updated 14 times

Summary

This study tests whether adding 4 cycles of chemotherapy around the time of surgery can help prevent the spread of soft tissue sarcoma in people whose tumors are considered high-risk based on a genetic test. About 600 adults with resectable sarcoma will be screened, and 250 high-risk participants will be randomly assigned to standard care (surgery with or without radiation) or standard care plus chemotherapy. The main goal is to see if the chemo improves how long people live without the cancer spreading.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • CHRU Besançon

    RECRUITING

    Besançon, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHU Limoges

    RECRUITING

    Limoges, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHU Marseille

    RECRUITING

    Marseille, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHU Poitiers

    RECRUITING

    Poitiers, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Centre Antoine Lacassagne

    RECRUITING

    Nice, 06189, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Centre Eugène Marquis

    RECRUITING

    Rennes, 35042, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Centre François Baclesse

    RECRUITING

    Caen, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Centre Georges-François Leclerc

    RECRUITING

    Dijon, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Centre Henri Becquerel

    RECRUITING

    Rouen, 76038, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Centre Jean Perrin

    RECRUITING

    Clermont-Ferrand, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Centre Léon Bérard

    RECRUITING

    Lyon, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hôpital Cochin

    RECRUITING

    Paris, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hôpitaux Universitaires de Strasbourg

    RECRUITING

    Strasbourg, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Institut Godinot

    RECRUITING

    Reims, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Institut Paoli-Calmettes

    RECRUITING

    Marseille, 13273, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Institut Universitaire du Cancer Toulouse Oncopole

    RECRUITING

    Toulouse, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Institut de Cancérologie de Lorraine - Centre Alexis Vautrin

    RECRUITING

    Vandœuvre-lès-Nancy, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Institut de Cancérologie de Montpellier

    RECRUITING

    Montpellier, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Institut de Cancérologie de l'Ouest

    RECRUITING

    Saint-Herblain, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.