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Blood test may predict who benefits from targeted radiation therapy

NCT ID NCT06876532

First seen Nov 01, 2025

Summary

This study looks at whether an inflammation-based score (using CRP and albumin levels) can predict how well patients with advanced intestinal neuroendocrine tumors respond to Lu-177 oxodotreotide therapy. Researchers will follow 150 patients for 36 months, collecting blood samples and imaging data. The goal is to see if a simple, non-invasive test can help identify who is most likely to benefit from this treatment.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • CHU Hôtel Dieu

    RECRUITING

    Nantes, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHU de Bordeaux

    NOT_YET_RECRUITING

    Bordeaux, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHU de Lille

    RECRUITING

    Lille, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHU de Lyon

    NOT_YET_RECRUITING

    Lyon, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHU de Poitiers

    NOT_YET_RECRUITING

    Poitiers, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Centre François Baclesse

    RECRUITING

    Caen, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hôpital La Timone

    NOT_YET_RECRUITING

    Marseille, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • IUCT-O

    RECRUITING

    Toulouse, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Institut de Cancérologie de l'Ouest

    NOT_YET_RECRUITING

    Angers, 49055, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Lu-177 oxodotreotide (a radioactive drug given as standard treatment)

What this could lead to

If successful, this could give doctors a simple blood test to predict which patients will respond to Lu-177 therapy, helping personalize treatment decisions.

What could go wrong

This is an observational study, not a treatment trial. The inflammation score is experimental and may not prove accurate enough for routine use.

Conditions

The condition(s) this trial relates to.

intestinal neuroendocrine neoplasm intestinal neuroendocrine tumor G1

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.