Scientists track rare gene mutation to predict blood cancer in families
NCT ID NCT06022016
First seen Jan 05, 2026 · Last updated Jun 23, 2026 · Updated 30 times
Summary
This study looks at families who carry a change in the DDX41 gene, which may raise the risk of blood cancers like leukemia. Researchers will collect health questionnaires and saliva samples from up to 910 people to track who develops blood problems and when. The goal is to better understand the risk and eventually create guidelines for monitoring and counseling these families.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Chu de Bordeaux
RECRUITINGBordeaux, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Chu de Limoges
RECRUITINGLimoges, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Chu de Montpellier
RECRUITINGMontpellier, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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IUCT-O
RECRUITINGToulouse, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Institut Paoli-Calmettes
RECRUITINGMarseille, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this study could lead to better genetic counseling and screening guidelines for families with DDX41 mutations, helping to catch blood cancers earlier.
What could go wrong
This is an observational study, not a treatment trial. It will not directly improve health, and results may take years to translate into clinical practice.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.