Scientists track rare gene mutation to predict blood cancer in families
NCT ID NCT06022016
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at families who carry a change in the DDX41 gene, which may raise the risk of blood cancers like leukemia. Researchers will collect health questionnaires and saliva samples from up to 910 people to track who develops blood problems and when. The goal is to better understand the risk and eventually create guidelines for monitoring and counseling these families.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this study could lead to better genetic counseling and screening guidelines for families with DDX41 mutations, helping to catch blood cancers earlier.
- What could go wrong
- This is an observational study, not a treatment trial. It will not directly improve health, and results may take years to translate into clinical practice.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Chu de Bordeaux
RECRUITINGBordeaux, France
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Chu de Limoges
RECRUITINGLimoges, France
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Chu de Montpellier
RECRUITINGMontpellier, France
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IUCT-O
RECRUITINGToulouse, France
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Institut Paoli-Calmettes
RECRUITINGMarseille, France
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