AI and big data join the fight against childhood brain cancer relapse
NCT ID NCT05151718
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looks back at data from 370 children treated for ependymoma, a common brain tumor in kids. Even after surgery and radiation, about half of these tumors return. Researchers are using artificial intelligence to analyze medical images, genetics, and treatment records to find clues that predict relapse. The goal is to design smarter radiation plans that target the tumor more precisely and prevent it from coming back.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could lead to more precise radiation therapy for children with ependymoma, potentially reducing relapse rates.
- What could go wrong
- This is an observational study analyzing existing data, not testing a new treatment. The findings may not translate into immediate clinical changes.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 370 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Sep 2021
- Expected to finish
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Sep 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Children with intracranial ependymoma treated in France since 2000 (included in PEPPI study between 2000 and 2013 and in pediaRT and french SIOP II programme since 2013)
- Ages
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Up to 25 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * children with intracranial ependymoma * treated * included in PEPPI study, pediaRT or in SIOP II Ependymoma french program Exclusion Criteria: * NA
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Institut Claudius Regaud
RECRUITINGToulouse, 31059, France
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